• Hepatitis C Virus Driven AXL Expression Suppresses the Hepatic Type I Interferon Response 

      Read, Scott A; Tay, Enoch; Shahidi, Mahsa; O'Connor, Kate; Booth, David; George, Jacob; Douglas, Mark
      Published 2015-01-01
      Treatment of chronic hepatitis C virus (HCV) infection is evolving rapidly with the development of novel direct acting antivirals (DAAs), however viral clearance remains intimately linked to the hepatic innate immune system. ...
      Open Access
      Article
    • Hepatitis C Virus Induces the Cannabinoid Receptor 1 

      van der Poorten, David; Shahidi, Mahsa; Tay, Enoch; Sesha, Jayshree; Tran, Kayla; McLeod, Duncan; Milliken, J; Ho, Vicki; Hebbard, Lionel; Douglas, Mark; George, Jacob
      Published 2010-01-01
      Background: Activation of hepatic CB1 receptors (CB1) is associated with steatosis and fibrosis in experimental forms of liver disease. However, CB1 expression has not been assessed in patients with chronic hepatitis C ...
      Open Access
      Article