Browsing by author "O’Neill, Geraldine M."
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Occupy tissue: the movement in cancer metastasis
Bradbury, Peta; Fabry, Ben; O’Neill, Geraldine M.Published 2012-09-01The critical role of migration and invasion in cancer metastasis warrants new therapeutic approaches targeting the machinery regulating cell migration and invasion. While 2-dimensional (2D) models have helped identify a ...Open AccessArticle -
Tropomyosin Regulates Cell Migration during Skin Wound Healing
Lees, Justin G.; Ching, Yu Wooi; Adams, Damian H.; Bach, Cuc T.T.; Samuel, Michael S.; Kee, Anthony J.; Hardeman, Edna C.; Gunning, Peter; Cowin, Allison J.; O’Neill, Geraldine M.Published 2015-05-01Precise orchestration of actin polymer into filaments with distinct characteristics of stability, bundling, and branching underpins cell migration. A key regulator of actin filament specialization is the tropomyosin family ...Open AccessArticle -
Tyrosine Y189 in the Substrate Domain of the Adhesion Docking Protein NEDD9 Is Conserved with p130Cas Y253 and Regulates NEDD9-Mediated Migration and Focal Adhesion Dynamics
Baquiran, Jaime B.; Bradbury, Peta; O’Neill, Geraldine M.Published 2013-07-09The focal adhesion docking protein NEDD9/HEF1/Cas-L regulates cell migration and cancer invasion. NEDD9 is a member of the Cas family of proteins that share conserved overall protein-protein interaction domain structure, ...Open AccessArticle
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