Browsing by author "O'Connell, Rachel"
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Efficacy and safety of LDL-lowering therapy among men and women: meta-analysis of individual data from 174,000 participants in 27 randomised trials
Cholesterol Treatment Trialists’ (CTT) Collaboration; Fulcher, Jordan; O'Connell, Rachel; Voysey, Merryn; Emberson, Jonathan; Blackwell, Lisa; Mihaylova, Borislava; Simes, John; Collins, Rory; Kirby, Adrienne; Colhoun, Helen; Braunwald, Eugene; LaRosa, John; Pedersen, TR; Tonkin, Andrew; Davis, Barry; Slright, Peter; Franzosi, Maria Grazia; Baigent, Colin; Keech, AnthonyPublished 2015-01-09Background Whether statin therapy is as effective in women as in men is debated, especially for primary prevention. We undertook a meta-analysis of statin trials in the Cholesterol Treatment Trialists' (CTT) Collaboration ...Open AccessArticle -
Long-term glycaemic variability and vascular complications in Type 2 diabetes: Post hoc analysis of the randomised, placebo controlled FIELD study
Scott, Emma; Januszewski, Andrzej S.; O'Connell, Rachel; Fulcher, Gregory; Scott, Russell; Kesaniemi, Antero; Wu, Linda; Colagiuri, Stephen; Keech, Anthony; Jenkins, Alicia J.Published 2020-04-01Aims: To investigate whether long-term glycaemic variability (GV) is associated with vascular complication development in Type 2 diabetes Methods: In a post-hoc FIELD trial analysis, GV was calculated as the standard ...Open AccessArticle -
The relationship of fibroblast growth factor 21 with cardiovascular outcome events in the Fenofibrate Intervention and Event Lowering in Diabetes study
Ong, Kwok-Leung; Januszewski, Andrzej S; O'Connell, Rachel; Jenkins, Alicia J; Xu, Aimin; Sullivan, David R; Barter, Philip J; Hung, Wei-Ting; Scott, Russell S; Taskinen, Marja-Riitta; Keech, Anthony C; Rye, Kerry-AnnePublished 2014-11-26Aims/hypothesis Circulating fibroblast growth factor 21 (FGF21) levels are often elevated in obesity, dyslipidaemia, insulin resistance and type 2 diabetes. This study investigated the relationship of plasma FGF21 levels ...Open AccessArticle
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