Browsing by author "McLachlan, Andrew"
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Efficacy and safety of antidepressants for the treatment of low back pain and osteoarthritis: protocol for a systematic review and meta-analysis
Ferreira, Giovanni; Lin, Chung-Wei Christine; Zadro, Joshua R; O'Keeffe, Mary; Shaheed, Christina Abdel; McLachlan, Andrew; Maher, Chris GPublished 2020Objectives: To systematically review the efficacy and safety of antidepressants for patients with spinal pain (including sciatica) and osteoarthritis of the hip and knee. Eligibility criteria: We will include randomised ...Preprint -
Protocol for the Controlled evaLuation of Angiotensin Receptor blockers for COVID-19 respIraTorY disease (CLARITY): a randomised controlled trial
Hockham, Carinna; Kotwal, Sradha; Wilcox, Arlen; Bassi, Abhinav; McGree, James; Pollock, Carol; Burrell, Louise M.; Bathla, Nikita; Kunigari, Mallikarjuna; Rathore, Vinay; John, Michael; Lin, Enmoore; Jenkins, Christine; Ritchie, Angus; McLachlan, Andrew; Snelling, Thomas; Jones, Mark; Jha, Vivekanand; Jardine, Meg;Published 2021BackgroundSARS-CoV-2 binds to membrane-bound angiotensin-converting enzyme 2 (ACE2) which may result in downregulation of membrane-bound ACE2. ACE2 is a key regulator of the renin-angiotensin system (RAS) and is responsible ...Article
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