Browsing by author "Mathieson, Ellen"
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BET Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV-2 Infection
Mills, Richard J.; Humphrey, Sean J.; Fortuna, Patrick RJ.; Lor, Mary; Foster, Simon R.; Quaife-Ryan, Gregory A.; Johnston, Rebecca L.; Dumenil, Troy; Bishop, Cameron; Ruraraju, Rajeev; Rawle, Daniel J.; Le, Thuy; Zhao, Wei; Lee, Leo; Mackenzie-Kludas, Charley; Mehdiabadi, Neda R.; Halliday, Christopher; Gilham, Dean; Fu, Li; Nicholls, Stephen J.; Johansson, Jan; Sweeney, Michael; Wong, Norman C.W.; Kulikowski, Ewelina; Sokolowski, Kamil A.; Tse, Brian W.C.; Devilée, Lynn; Voges, Holly K.; Reynolds, Liam T.; Krumeich, Sophie; Mathieson, Ellen; Abu-Bonsrah, Dad; Karavendzas, Kathy; Griffen, Brendan; Titmarsh, Drew; Elliott, David A.; McMahon, James; Suhrbier, Andreas; Subbarao, Kanta; Porrello, Enzo R.; Smyth, Mark J.; Engwerda, Christian R.; MacDonald, Kelli PA.; Bald, Tobias; James, David E.; Hudson, James E.Published 2021Cardiac injury and dysfunction occur in COVID-19 patients and increase the risk of mortality. Causes are ill defined, but could be direct cardiac infection and/or inflammation-induced dysfunction. To identify mechanisms ...Article -
Discovery of drugs to treat cytokine storm-induced cardiac dysfunction using human cardiac organoids
Mills, Richard J; Humphrey, Sean J; Fortuna, Patrick RJ; Quaife-Ryan, Gregory A; Mehdiabadi, Neda R; Devilée, Lynn; Voges, Holly K; Reynolds, Liam T; Krumeich, Sophie; Mathieson, Ellen; Griffen, Brendan; Titmarsh, Drew; Porrello, Enzo R; Smyth, Mark J; Engwerda, Christian R; MacDonald, Kelli PA; Bald, Tobias; James, David E; Hudson, James EPublished 2020SUMMARY SARS-CoV2 infection leads to cardiac injury and dysfunction in 20-30% of hospitalized patients 1 and higher rates of mortality in patients with pre-existing cardiovascular disease 2,3 . Inflammatory factors released ...Preprint
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