• ASCOT ADAPT study of COVID-19 therapeutics in hospitalised patients: an international multicentre adaptive platform trial 

      Denholm, Justin T; Venkatesh, Balasubramanian; Davis, Joshua; Bowen, Asha C.; Hammond, Naomi E; Jha, Vivekanand; McPhee, Grace; McQuilten, Zoe; O'Sullivan, Matthew VN; Paterson, David; Price, David; Rees, Megan; Roberts, Jason; Jones, Mark; Totterdell, James; Snelling, Thomas; Trask, Nanette; Morpeth, Susan; Tong, Steven YC
      Published 2022
      Background SARS-CoV-2 infection is associated with a significant risk of hospitalisation, death, and prolonged impact on quality of life. Evaluation of new treatment options and optimising therapeutic management of people ...
      Preprint
    • Ethics of kidney care in the era of COVID-19 

      Martin, Dominique E.; Parsons, Jordan A.; Caskey, Fergus; Harris, David C.H.; Jha, Vivekanand
      Published 2020
      The COVID-19 pandemic presents significant challenges for health systems globally, including substantive ethical dilemmas that may pose specific concerns in the context of care for people with kidney disease. Ethical ...
      Article
    • International collaborative efforts to establish kidney health surveillance systems 

      Hole, Barnaby D; Evans, Katharine M; Pyart, Rhodri; Davids, M Razeen; Bedat, Carlota Gonzalez; Hanafusa, Norio; Harris, David C H; Jager, Kitty J; Jha, Vivekanand; Johansen, Kirsten L; McDonald, Stephen; Masakane, Ikuto; Rosa-Diez, Guillermo; Saran, Rajiv; Wetmore, James B; Caskey, Fergus J
      Published 2020
      Article
    • Protocol for the Controlled evaLuation of Angiotensin Receptor blockers for COVID-19 respIraTorY disease (CLARITY): a randomised controlled trial 

      Hockham, Carinna; Kotwal, Sradha; Wilcox, Arlen; Bassi, Abhinav; McGree, James; Pollock, Carol; Burrell, Louise M.; Bathla, Nikita; Kunigari, Mallikarjuna; Rathore, Vinay; John, Michael; Lin, Enmoore; Jenkins, Christine; Ritchie, Angus; McLachlan, Andrew; Snelling, Thomas; Jones, Mark; Jha, Vivekanand; Jardine, Meg;
      Published 2021
      BackgroundSARS-CoV-2 binds to membrane-bound angiotensin-converting enzyme 2 (ACE2) which may result in downregulation of membrane-bound ACE2. ACE2 is a key regulator of the renin-angiotensin system (RAS) and is responsible ...
      Article
    • Providing care for patients with kidney failure over the next decade 

      Harris, David C.H.; Davies, Simon J.; Finkelstein, Fredric O.; Jha, Vivekanand; Donner, Jo-Ann
      Published 2020
      Article
    • Strategic plan for integrated care of patients with kidney failure 

      Harris, David C.H.; Davies, Simon J.; Finkelstein, Fredric O.; Jha, Vivekanand; Bello, Aminu K.; Brown, Mark; Caskey, Fergus J.; Donner, Jo-Ann; Liew, Adrian; Muller, Elmi; Naicker, Saraladevi; O'Connell, Philip J.; Filho, Roberto Pecoits; Vachharajani, Tushar; Groups, Strategic Plan Working; Abu Alfa, Ali K.; Ashuntantang, Gloria; Brown, Edwina; Cullis, Brett; Dreyer, Gavin; Eke, Felicia U.; Garcia, Guillermo Garcia; Goh, Bak Leong; Hemmelgarn, Brenda; Hou, Fan Fan; Iyengar, Arpana; Johnson, David W.; Levin, Nathan W.; Luyckx, Valerie A.; Martin, Dominique E.; McCulloch, Mignon I.; Mengistu, Yewondwossesn Tadesse; Moosa, Mohammed Rafique; Morton, Rachael L.; Niang, Abdou; Obrador, Gregorio T.; Okpechi, Ikechi G.; Ossareh, Shahrzad; Shah, Kamal D.; Sola, Laura; Swanepoel, Charles; Tchokhonelidze, Irma; Tonelli, Marcello; Trask, Michele; Kazancioglu, Rumeyza Turan; Twahir, Ahmed; Walker, Robert; Were, Anthony J.O.; Yang, Chih-Wei; Yeates, Karen; Zakharova, Elena; Zuniga, Carlos
      Published 2020
      There is a huge gap between the number of patients worldwide requiring versus those actually receiving safe, sustainable, and equitable care for kidney failure. To address this, the International Society of Nephrology ...
      Article