Browsing by author "Hardcastle, N"
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4-Dimensional Cone Beam Computed Tomography-Measured Target Motion Underrepresents Actual Motion
Steiner, E; Shieh, CC; Caillet, V; Booth, J; Hardcastle, N; Briggs, A; Jayamanne, D; Haddad, C; Eade, T; Keall, PPublished 2018-11-15PURPOSE: Four-dimensional cone beam computed tomography (4DCBCT) facilitates verification of lung tumor motion before each treatment fraction and enables accurate patient setup in lung stereotactic ablative body radiation ...Open AccessArticle -
The Accuracy and Precision of the KIM Motion Monitoring System Used in the Multi-Institutional TROG 15.01 Stereotactic Prostate Ablative Radiotherapy With KIM (SPARK) Trial
Hewson, E; Nguyen, DT; O'Brien, R; Kim, J-H; Montanaro, T; Moodie, T; Greer, P; Hardcastle, N; Eade, T; Kneebone, A; Hruby, G; Hayden, A; Turner, S; Siva, S; Tai, K-H; Hunter, P; Sams, J; Poulsen, P; Booth, J; Martin, J; Keall, PPublished 2019-01-01Purpose: Kilovoltage intrafraction monitoring (KIM) allows for real-time image guidance for tracking tumor motion in six-degrees-of-freedom (6DoF) on a standard linear accelerator. This study assessed the geometric accuracy ...Open AccessArticle -
An augmented correlation framework for the estimation of tumour translational and rotational motion during external beam radiotherapy treatments using intermittent monoscopic x-ray imaging and an external respiratory signal.
Nguyen, DT; Booth, JT; Caillet, V; Hardcastle, N; Briggs, A; Hadad, C; Eade, T; O'Brien, R; Keall, PPublished 2018-10-01Increasing evidence shows that intrafraction tumour motion monitoring must include both six degrees of freedom (6DoF): 3D translations and 3D rotations. Existing real-time algorithms for 6DoF target motion estimation require ...Open AccessArticle -
Both four-dimensional computed tomography and four-dimensional cone beam computed tomography under-predict lung target motion during radiotherapy.
Steiner, E; Shieh, CC; Caillet, V; Booth, J; O'Brien, R; Briggs, A; Hardcastle, N; Jayamanne, D; Szmura, K; Eade, T; Keall, PPublished 2019-06-01BACKGROUND AND PURPOSE: To test the hypothesis that 4DCT and 4DCBCT-measured target motion ranges predict target motion ranges during lung cancer SABR. MATERIALS AND METHODS: Ten lung SABR patients were implanted with ...Open AccessArticle -
Dose enhancement in radiotherapy of small lung tumors using inline magnetic fields: A Monte Carlo based planning study
Oborn, B; Ge, Y; Hardcastle, N; Metcalfe, P; Keall, PPublished 2016-01-01PURPOSE: To report on significant dose enhancement effects caused by magnetic fields aligned parallel to 6 MV photon beam radiotherapy of small lung tumors. Findings are applicable to future inline MRI-guided radiotherapy ...Open AccessArticle -
Experimental verification of dose enhancement effects in a lung phantom from inline magnetic fields.
Oborn, B; Gargett, MA; Causer, TJ; Alnaghy, SJ; Hardcastle, N; Metcalfe, PE; Keall, PPublished 2017-12-01BACKGROUND AND PURPOSE: To present experimental evidence of lung dose enhancement effects caused by strong inline magnetic fields. MATERIALS AND METHODS: A permanent magnet device was utilised to generate 0.95T-1.2T magnetic ...Open AccessArticle -
The first patient treatment of electromagnetic-guided real time adaptive radiotherapy using MLC tracking for lung SABR.
Booth, JT; Caillet, V; Hardcastle, N; O'Brien, R; Szymura, K; Crasta, C; Harris, B; Haddad, C; Eade, T; Keall, PPublished 2016-10-01BACKGROUND AND PURPOSE: Real time adaptive radiotherapy that enables smaller irradiated volumes may reduce pulmonary toxicity. We report on the first patient treatment of electromagnetic-guided real time adaptive radiotherapy ...Open AccessArticle -
Geometric uncertainty analysis of MLC tracking for lung SABR.
Caillet, V; Zwan, B; Briggs, A; Hardcastle, N; Szymura, K; Prodreka, A; O'Brien, R; Harris, BE; Greer, P; Haddad, C; Jayamanne, D; Eade, T; Booth, J; Keall, PPublished 2020Purpose: The purpose of this work was to report on the geometric uncertainty for patients treated with multi-leaf collimator (MLC) tracking for lung SABR to verify the accuracy of the system. Methods: Seventeen patients ...Open AccessArticle -
MLC tracking for lung SABR reduces planning target volumes and dose to organs at risk.
Caillet, V; Keall, P; Colvill, E; Hardcastle, N; O'Brien, R; Szymura, K; Booth, JTPublished 2017-07-01PURPOSE: Assess the dosimetric impact of multi-leaf collimator (MLC) tracking and mid-ventilation (midV) planning compared with the internal target volume (ITV)-based planning approach for lung Stereotactic Ablative Body ...Open AccessArticle -
Quantification of the geometric uncertainty when using implanted markers as a surrogate for lung tumor motion.
Hardcastle, N; Briggs, A; Caillet, V; Angelis, G; Chrystall, D; Jayamanne, D; Shepherd, M; Harris, B; Haddad, C; Eade, T; Keall, P; Booth, JPublished 2021Background: Fiducial markers are used as surrogates for tumor location during radiation therapy treatment. Developments in lung fiducial marker and implantation technology have provided a means to insert markers endobronchially ...Open AccessArticle
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