Browsing by author "Glasziou, Paul"
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16 The burden of cancer overdiagnosis in Australia
Glasziou, Paul; Jones, Mark; Pathirana, Thanya; Barratt, Alexandra L; Bell, Katy J.L.Published 2019Burden of cancer is increasing worldwide, and in Australia, partly due to overdiagnosis: cancers which would never cause symptoms or harm if left undetected. We sought to estimate the current burden of overdiagnosis of ...Presentation -
23 Heart age: intuitive communication tool or gateway to overdiagnosis? A comparison of 3 countries
Bonner, Carissa; McKinn, Shannon; McCaffery, Kirsten; Glasziou, Paul; Doust, Jenny; Jansen, Jesse; Bell, Katy J.L.Published 2019Heart age calculators are increasingly popular around the world as a way to promote and communicate cardiovascular disease (CVD) risk assessment to patients/consumers. While they have intuitive appeal, the implicit assumptions ...Presentation -
89 Incremental benefits and harms of the 2017 american college of cardiology/american heart association high blood pressure guideline
Bell, Katy J.L.; Doust, Jenny; Glasziou, PaulPublished 2018The recent recommendations from the American College of Cardiology and the American Heart Association (ACC/AHA) to lower the thresholds for defining hypertension follows a general pattern across medical specialties, whereby ...Conference paper -
Analyses within risk strata overestimate gain in discrimination: the example of coronary artery calcium scores
Zhu, Lin; Bell, Katy J.L.; Scott, Anna Mae; Glasziou, PaulPublished 2022Risk prediction models are potentially useful tools for health practitioners and policy makers. When new predictors are proposed to add to existing models, the improvement of discrimination is one of the main measures to ...Open AccessReport, Research -
Approaches to prioritising research for clinical trial networks: a scoping review
Morton, Rachael L.; Tuffaha, Haitham; Blaya-Novakova, Vendula; Spencer, Jenean; Hawley, Carmel M.; Peyton, Phil; Higgins, Alisa; Marsh, Julie; Taylor, William J.; Huckson, Sue; Sillett, Amy; Schneemann, Kieran; Balagurunanthan, Anitha; Cumpston, Miranda; Scuffham, Paul A.; Glasziou, Paul; Simes, Robert J.Published 2022Background Prioritisation of clinical trials ensures that the research conducted meets the needs of stakeholders, makes the best use of resources and avoids duplication. The aim of this review was to identify and critically ...Open AccessArticle -
Assessment of changes to screening programmes: why randomisation is important
Bell, Katy J.L.; Bossuyt, Patrick; Glasziou, Paul; Irwig, LesPublished 2015Screening programmes sometimes need to be adapted as new technologies and treatments become available. Katy Bell and colleagues argue the best way to assess such changes is through randomised trials within the programmesArticle -
Communicating cardiovascular disease risk: an interview study of General Practitioners’ use of absolute risk within tailored communication strategies
Bonner, Carissa; Jansen, Jesse; McKinn, Shannon; Irwig, Les; Doust, Jenny; Glasziou, Paul; McCaffery, KirstenPublished 2014-05-29Background: Cardiovascular disease (CVD) prevention guidelines encourage assessment of absolute CVD risk - the probability of a CVD event within a fixed time period, based on the most predictive risk factors. However, few ...Open AccessArticle -
Comparison of seroprevalence of SARS-CoV-2 infections with cumulative and imputed COVID-19 cases: systematic review
Byambasuren, Oyungerel; Dobler, Claudia C; Bell, Katy J.L.; Rojas, Diana P; Clark, Justin; McLaws, Mary-Louise; Glasziou, PaulPublished 2021Accurate seroprevalence estimates of SARS-CoV-2 in different populations could clarify the extent to which current testing strategies are identifying all active infection, and hence the true magnitude and spread of the ...Open AccessArticle -
A Counterargument to Encounter Frequency and Target Achievement: Measurement Variability
Hayen, Andrew; Bell, Katy J.L.; Glasziou, Paul; Irwig, LesPublished 2012Editorial response to the conclusion of the recent report by Morrison and colleagues that encounter frequency leads to apparent better control of glucose (hemoglobin A1c), blood pressure, and low-density lipoprotein ...Article, Letter -
Criteria for monitoring tests were described: validity, responsiveness, detectability of long-term change, and practicality
Bell, Katy J.L.; Glasziou, Paul; Hayen, Andrew; Irwig, LesPublished 2014Objective: To describe how evidence from trials and cohort studies may be used to guide choice of test for monitoring patients with chronic disease. Study Design and Setting: Exploration of potential criteria for ...Article -
Early CRT monitoring using time-domain optical coherence tomography does not add to visual acuity for predicting visual loss in patients with central retinal vein occlusion treated with intravitreal Ranibizumab
Bell, Katy J.L.; Hayen, Andrew; Glasziou, Paul; Mitchell, Andrew S; Farris, Maria; Wright, Jonathan; Duerr, Hans-Peter; Mitchell, Paul; Irwig, LesPublished 2017Our primary purpose was to assess the clinical (predictive) validity of central retinal thickness (CRT) and best corrected visual acuity (BCVA) at 1 week and 1 month after starting treatment with ranibizumab for central ...Open AccessArticle -
Effects of fenofibrate on cardiovascular events in patients with diabetes, with and without prior cardiovascular disease: The Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study
Tonkin, Andrew; Hunt, David; Voysey, Merryn; Kesäniemi, Antero; Hamer, Andrew; Waites, Jonathon; Maher, Leo; Mann, Stewart; Glasziou, Paul; Forder, Peta; Simes, John; Keech, AnthonyPublished 2012-02-01Background In the FIELD study, comparison of the effect of fenofibrate on cardiovascular disease (CVD) between those with prior CVD and without was a prespecified subgroup analysis. Methods The effects of fenofibrate on ...Open AccessArticle -
Effects of fenofibrate on renal function in patients with type 2 diabetes mellitus: the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) Study
Davis, Timothy ME; Ting, Ru-Dee; Best, James D; Donoghoe, Mark; Drury, Paul L; Sullivan, David R; Jenkins, Alicia J; O'Connell, Rachel L; Whiting, Malcolm; Glasziou, Paul; Simes, R John; Kesaniemi, Y Antero; Gebski, Val; Scott, Russell; Keech, Anthony CPublished 2011-02-01Abstract Aims/hypothesis Fenofibrate caused an acute, sustained plasma creatinine increase in the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) and Action to Control Cardiovascular Risk in Diabetes ...Open AccessPost-print -
Equity and evidence during vaccine rollout: stepped wedge cluster randomised trials could help.
Bell, Katy J.L.; Glasziou, Paul; Stanaway, Fiona; Bossuyt, Patrick; Irwig, LesPublished 2021Letter re allocating scarce vaccines, For groups of equivalent priority, a fair and equitable way to decide on the order of rollout is to use a lottery, or system of random choice. Such randomised sequentialrollout of ...Open AccessArticle -
Estimating the extent of asymptomatic COVID-19 and its potential for community transmission: Systematic review and meta-analysis
Byambasuren, Oyungerel; Cardona, Magnolia; Bell, Katy J.L.; Clark, Justin; McLaws, Mary-Louise; Glasziou, PaulPublished 2020Background: Knowing the prevalence of true asymptomatic coronavirus disease 2019 (COVID-19) cases is critical for designing mitigation measures against the pandemic. We aimed to synthesize all available research on ...Article -
Estimating the extent of asymptomatic COVID-19 and its potential for community transmission: systematic review and meta-analysis
Byambasuren, Oyungerel; Cardona, Magnolia; Bell, Katy J.L.; Clark, Justin; McLaws, Mary-Louise; Glasziou, PaulPublished 2020Background: The prevalence of true asymptomatic COVID-19 cases is critical to policy makers considering the effectiveness of mitigation measures against the SARS-CoV-2 pandemic. We aimed to synthesize all available research ...Preprint -
Estimating the magnitude of cancer overdiagnosis in Australia
Glasziou, Paul; Jones, Mark A; Pathirana, Thanya; Barratt, Alexandra L; Bell, Katy J.L.Published 2019This study aimed to estimate the proportion of cancer diagnoses in Australia that might reasonably be attributed to overdiagnosis by comparing current and past lifetime risks of cancer. Routinely collected Australian ...Open AccessArticle -
Evaluation of the Incremental Value of a Coronary Artery Calcium Score Beyond Traditional Cardiovascular Risk Assessment A Systematic Review and Meta-analysis
Bell, Katy J.L.; White, Sam; Hassan, Omar; Zhu, Lin; Scott, Anna Mae; Clark, Justin; Glasziou, PaulPublished 2022Coronary artery calcium scores (CACS) are used to help assess patients’ cardiovascular status and risk. However, their best use in risk assessment beyond traditional cardiovascular factors in primary prevention is ...Open AccessArticle -
Examining Australian’s beliefs, misconceptions and sources of information for COVID-19: a national online survey
Thomas, Rae; Greenwood, Hannah; Michaleff, Zoe A; Abukmail, Eman; Hoffmann, Tammy C; McCaffery, Kirsten; Hardiman, Leah; Glasziou, PaulPublished 2021OBJECTIVE: Public cooperation to practise preventive health behaviours is essential to manage the transmission of infectious diseases such as COVID-19. We aimed to investigate beliefs about COVID-19 diagnosis, transmission ...Article -
Factors influencing general practitioners’ decisions about cardiovascular disease risk reassessment: findings from experimental and interview studies
McKinn, Shannon; Bonner, Carissa; Jansen, Jesse; Teixeira-Pinto, Armando; So, Matthew; Irwig, Les; Doust, Jenny; Glasziou, Paul; McCaffery, KirstenPublished 2016-08-05Background: Guidelines on cardiovascular disease (CVD) risk reassessment intervals are unclear, potentially leading to detrimental practice variation: too frequent can result in overtreatment and greater strain on the ...Open AccessArticle
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