Browsing by author "Denholm, Justin T"
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ASCOT ADAPT study of COVID-19 therapeutics in hospitalised patients: an international multicentre adaptive platform trial
Denholm, Justin T; Venkatesh, Balasubramanian; Davis, Joshua; Bowen, Asha C.; Hammond, Naomi E; Jha, Vivekanand; McPhee, Grace; McQuilten, Zoe; O'Sullivan, Matthew VN; Paterson, David; Price, David; Rees, Megan; Roberts, Jason; Jones, Mark; Totterdell, James; Snelling, Thomas; Trask, Nanette; Morpeth, Susan; Tong, Steven YCPublished 2022Background SARS-CoV-2 infection is associated with a significant risk of hospitalisation, death, and prolonged impact on quality of life. Evaluation of new treatment options and optimising therapeutic management of people ...Preprint -
Integrated immune dynamics define correlates of COVID-19 severity and antibody responses
Koutsakos, Marios; Rowntree, Louise C; Hensen, Luca; Chua, Brendon Y; van de Sandt, Carolien E; Habel, Jennifer R; Zhang, Wuji; Jia, Xiaoxiao; Kedzierski, Lukasz; Ashhurst, Thomas M; Putri, Givanna H; Marsh-Wakefield, Felix; Read, Mark N; Edwards, Davis N; Clemens, E Bridie; Wong, Chinn Yi; Mordant, Francesca L; Juno, Jennifer A; Amanat, Fatima; Audsley, Jennifer; Holmes, Natasha E; Gordon, Claire L; Smibert, Olivia C; Trubiano, Jason A; Hughes, Carly M; Catton, Mike; Denholm, Justin T; Tong, Steven Y C; Doolan, Denise L; Kotsimbos, Tom C; Jackson, David C; Krammer, Florian; Godfrey, Dale I; Chung, Amy W; King, Nicholas J C; Lewin, Sharon R; Wheatley, Adam K; Kent, Stephen J; Subbarao, Kanta; McMahon, James; Thevarajan, Irani; Nguyen, Thi H O; Cheng, Allen C; Kedzierska, KatherinePublished 2021SARS-CoV-2 causes a spectrum of COVID-19 disease, the immunological basis of which remains ill defined. We analyzed 85 SARS-CoV-2-infected individuals at acute and/or convalescent time points, up to 102 days after symptom ...Article
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