Browsing by author "Carvalho, Sílvia"
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Binding and transport properties of a benzo[b]thiophene-based mono-(thio)urea library
Moiteiro, Cristina; Marques, Igor; Ryder, William G.; Cachatra, Vasco; Carvalho, Sílvia; Chen, Li-Jun; Goodfellow, Brian J.; Gale, Philip A.; Félix, VítorPublished 2021Using the chemical versatility of the benzo[ b ]thiophene motif, an extensive library of 24 (thio)urea receptors, with different binding properties and lipophilicities was prepared and included α,α-, α,β-, β,β-, β,γ-, α,γ-, ...Open AccessArticle -
Development of a library of thiophene-based drug-like LEGO molecules: evaluation of their anion binding, transport properties and cytotoxicity
Vieira, Paulo; Miranda, Margarida Q.; Marques, Igor; Carvalho, Sílvia; Li-Jun, Chen; Howe, Ethan N.W.; Zhen, Carl; Leung, Claudia Y.; Spooner, Michael J.; Morgado, Bárbara; da Cruz e Silva, Odete A.B.; Moiteiro, Cristina; Gale, Philip A.; Félix, VítorPublished 2020-01-01The anion binding and transport properties of an extensive library of thiophene-based molecules are reported. Seventeen bis-urea positional isomers, with different binding conformations and lipophilicities, were synthetized ...Open AccessArticle
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