Browsing Sydney Digital Theses (University of Sydney Access only) by title
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Vaccine induced protection: Examining the immune-profile of vaccinated livestock exposed to Mycobacterium avium subsp. paratuberculosis
Published 2017-09-28Paratuberculosis is a chronic wastage disease of ruminants caused by Mycobacterium avium subspecies paratuberculosis (MAP), a facultative intracellular bacterium. The disease is a significant financial burden with combined ...Thesis -
Validation of IRBP as a retinal treatment target and screening for human photoreceptor-specific nanoparticles for CRISPRa gene therapy
Published 2024My research focuses on a protein called interphotoreceptor retinoid-binding protein (IRBP), which is important for eye health. Problems with this protein can lead to retinal degeneration, a serious eye condition. I ...Thesis -
Validation of surrogate endpoints used in clinical trials of immune checkpoint inhibitors and targeted therapies in advanced cancers
Published 2023This thesis evaluated the validity of surrogate endpoints used in trials of immune checkpoint inhibitors (ICIs) and molecular targeted therapies in advanced cancers. Many recent regulatory approvals of these novel agents ...Thesis -
The validity of serological surveys and their use within a comprehensive surveillance system for vaccine preventable diseases in Australia
Published 2016-02-29With respect to vaccine-preventable diseases (VPDs), serological surveys are a special surveillance tool using the prevalence of disease-specific antibody to measure exposure to vaccination or infection in the population. ...Thesis -
Valorisation Of Peanut By-Products
Published 2018-03-29Rapid growth in the volume and variety of agro-industrial wastes along with the increasing demand for energy, chemicals and materials have fostered global research efforts to develop technologies with low environmental ...Thesis -
The Valuation of Dividends
Published 2020Much research has been done in relation to the market value of dividends, but this remains a debatable issue. In the Australian context, where relevant dividends have imputation tax credits attached, another unresolved ...Thesis -
The Valuation of Dividends
Published 2020Much research has been done in relation to the market value of dividends, but this remains a debatable issue. In the Australian context, where relevant dividends have imputation tax credits attached, another unresolved ...Thesis -
The value and impact of the International Baccalaureate Primary Years Programme in Two Australian Schools: Perceptions of students, teachers, administrators and parents
Published 2017-06-30The International Baccalaureate® (IB) aims to develop inquiring, knowledgeable and caring young people who help to create a better and more peaceful world through intercultural understanding and respect. It consists of ...Thesis -
The Value of Autonomy in Bioethics
Published 2020-01-01The requirement to respect patients’ autonomy is widely accepted in bioethics. However, what this means and what implications it has for medicine are unclear. Indeed, the focus on autonomy is often held to require that ...Thesis -
Valuing for Others: Centring Values in Proxy Decision Making
Published 2021Advance directives have proven inadequate as an advance care planning tool, largely because they fail to adequately anticipate and address relevant clinical scenarios. The primary response has been to turn to proxy ...Thesis -
Vanguard State: Labour, radicalism, and third-party politics in Minnesota, 1934-1944.
Published 2019-02-28This thesis examines the rise of industrial unions in Minnesota in the late 1930s and early 1940s by placing this within the broader context of state and local politics. In the 1930s, the influence of left-wing politics ...Thesis -
Variable-Twist Propellers for Small Unmanned Aerial Systems
Published 2020Small unmanned aerial systems are now often utilised in a wide range of military and civilian applications. However, propulsion technology development for these systems has lagged significantly. While most variable-pitch ...Thesis -
Variation of the Toll-like receptors in two marsupial species, Tasmanian devils, Sarcophilus harrisii, and Koalas, Phascolarctos cinereus
Published 2015-06-30Genetic diversity plays an important role in wildlife conservation, particularly genetic diversity in immune genes, as some genetic variants are able to contribute to disease resistance and susceptibility. Low genetic ...Thesis -
Variational Inference in Generalised Hyperbolic and von Mises-Fisher Distributions
Published 2015-12-17Most real world data are skewed, contain more than the set of real numbers, and have higher probabilities of extreme events occurring compared to a normal distribution. In this thesis we explore two non-Gaussian distributions, ...Thesis -
Variations in obstetric interventions in New South Wales, Australia
Published 2017-03-10Aims To describe variation in caesarean section (CS) and induction of labour (IOL) rates and outcomes; determine ways of classifying IOL; describe variation in current IOL methods. Methods A systemic review examined different ...Thesis -
Varicella Zoster Virus infection of human matured monocyte derived dendritic cells & its impact on their effector functions
Published 2015-01-05Varicella Zoster Virus (VZV) is a species specific alpha human herpes virus that causes both Varicella (chickenpox) and Herpes Zoster (shingles) in human hosts. It has been hypothesized that host dendritic cells (DC) play ...Thesis -
Vascular reconstruction with major pelvic and retroperitoneal malignancy resection
Published 2023Treatment of pelvic tumours which involve the aorto-iliac axis forms the basis of this thesis and is centred around the experience of the pelvic exenteration unit at Royal Prince Alfred Hospital, Sydney, Australia. Here ...Thesis -
Vehicles of informational content in neural networks
Published 2014-06-19Localizing content in neural networks provides a bridge to understanding the way in which the brain stores and processes information. A relatively powerful and yet accessible architectural setting in which to approach the ...Thesis -
Venereal Disease Control in the Progressive Era US Army: Managing Gendered Labour and Leisure in Militarised Space, 1870-1920
Published 2019-07-24This thesis shows how the US Army managed venereal disease in different military, racial, and geographic contexts between 1870 and 1920. It tracks local negotiations and wider shifts in practice and attitudes over the ...Thesis -
VENEZUELA DURING THE CHÁVEZ ERA (1999-2013) Participatory Democracy, Economic Planning, and the Contradictions of Oil Dependency
Published 2023This thesis examines the socio-economic and political consequences of Venezuela’s oil dependency during the tumultuous Chávez era (1999-2013), coinciding with two historically significant oil booms (2004-2008 and 2009-2014). ...Thesis