Browsing Sydney Digital Theses (University of Sydney Access only) by title
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Tailoring Redox Activity in Metal-Organic Frameworks (MOFs) to Unlock Emergent Electronic Behaviours
Published 2016-08-29This thesis reports an investigation into redox-active metal-organic frameworks (MOFs) from design principles through to structural, electrochemical, and spectroscopic insights into their unique electronic behaviours. The ...USyd AccessThesis -
Tailoring the phase and amplitude of optical signals using large Brillouin gain in photonic integrated circuits
Published 2018-01-07Microwave photonic devices based on stimulated Brillouin scattering offer unique functionalities evidenced by recent demonstrations of broadband tunable microwave filters with the potential for developing flexible and ...USyd AccessThesis -
Tailoring Weight Loss Regimens by Gender
Published 2023Background: Numerous studies have shown that the mean response to a weight loss intervention hides significant individual variation. Given the biological and physiological differences between males and females, we hypothesise ...USyd AccessThesis -
Take One of Everything: An Intellectual Biography of Donald Horne
Published 2021Donald Horne (1921–2005) was one of the most prominent Australian public intellectuals of the 1960s. His bestselling first book, The Lucky Country (1964), delivered a full-throated critique of Australian politics and society ...USyd AccessThesis -
Taking a health literacy and person-centred approach to improve translated diabetes self-management education materials
Published 2022Background: Little is known about health literacy of Australian-Chinese immigrants, or about the health literacy demands of translated materials. Aims: To assess the prevalence of lower health literacy among Australian-Chinese ...USyd AccessThesis -
Takotsubo Cardiomyopathy in the Intensive Care Unit
Published 2017-09-22Background Takotsubo cardiomyopathy (TC) is a syndrome of reversible left ventricular dysfunction triggered by psychological or physical stress. The pathogenesis is related to high levels of circulating catecholamines. ...USyd AccessThesis -
A Tale of Two Republics: Race, Rights and Revolution, 1919-1963.
Published 2017-11-11My dissertation maps African American and Francophone black intellectual collaborations over human rights and citizenship from 1919 until 1963. From the so-called Wilsonian moment associated with the Paris of 1919 until ...USyd AccessThesis -
Talking about talent: conceptualising talent management through discourse
Published 2014-12-18This thesis employs discourse analysis in order to understand how the concepts of “talent” and “talent management” are socially constructed within an organisational setting and the ways in which these are then brought into ...USyd AccessThesis -
Talking Into Foreignness: The impact of a sustained and intimate communication on the art of three artist couples.
Published 2015-11-23A study of three artist couples: their art, the communication of ideas between the artists in each pair, and the relation their enclave has to the wider art community. The artists are Marie Hagerty and Peter Vandermark, ...USyd AccessThesis -
Targeted Delivery of a Platinum Anticancer Complex to Tumours Using Carrier-DNA Tethered Aptamers
Published 2015-05-08DNA-based aptamers have been proposed as a simultaneous active targeting agent and delivery vehicle for anticancer drugs. PHENSS is a platinum-based anticancer complex that reversibly binds to DNA. Previous research has ...USyd AccessThesis -
Targeted therapies and immune checkpoint inhibitors in the treatment of metastatic melanoma patients
Published 2017-03-31The previously dismal prospects of patients with advanced stage metastatic melanoma have greatly improved in recent years. Enhanced understanding of both the pathogenesis of melanoma and its molecular drivers, as well as ...USyd AccessThesis -
Targeting HER2 in lung cancers
Published 2020Therapeutic targeting of human epidermal growth factor receptor 2 (HER2) has transformed the care of women with breast cancers with substantial improvement in survival. In contrast, lung cancers remain the leading cause ...USyd AccessThesis -
Targeting innate immunity as therapeutic strategy in diabetic nephropathy
Published 2017-02-28Diabetic nephropathy (DN) is the most common cause of both chronic kidney disease and end-stage kidney disease worldwide, which affects 30-40% of people with Type 1 or Type 2 diabetes. DN was initially considered to be a ...USyd AccessThesis -
Targeting innate immunity in acute kidney injury
Published 2022Acute kidney injury (AKI) is an umbrella term for various aetiological insults, disrupting the kidneys’ capacity to carry out many of its essential physiological function. We focused on the ischemia reperfusion injury (IRI) ...USyd AccessThesis -
Targeting KCa3.1 in diabetic tubulointerstitial fibrosis
Published 2014-04-30KCa3.1, a potassium channel protein, mediates cellular signaling processes associated with dysfunction of vasculature. However, the role of KCa3.1 in diabetic nephropathy has not been studied. In this thesis, human proximal ...USyd AccessThesis -
Targeting neuroinflammation to treat intractable brain disorders: studies in preclinical models of PTSD and epilepsy
Published 2022Aberrant neuroinflammation may become maladaptive and contribute to the pathophysiology of Posttraumatic Stress Disorder (PTSD) and Dravet syndrome, both brain disorders of which there is an unmet clinical need. Thus, this ...USyd AccessThesis -
Targeting non-alcoholic steatohepatitis induced by high fat feeding and type 2 diabetes in a preclinical model
Published 2015-12-30Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the developed world and it is strongly associated with metabolic derangements, such as insulin resistance, dyslipidaemia, obesity and ...USyd AccessThesis -
Targeting non-oncogenic kinases DYRK1A and MK2 in glioblastoma
Published 2020Glioblastoma represents the most common and aggressive primary brain tumour. Current treatment protocols however are mostly ineffective as all patients succumb to the disease within two years of diagnosis. Despite continued ...USyd AccessThesis -
Targeting protein trafficking pathways in melanoma
Published 2020-01-01Despite the recent breakthroughs in targeted drug- and immuno-therapies, late-stage melanoma patients still suffer from an abysmal prognosis due to development of drug resistance, enhanced toxicity and low response rates. ...USyd AccessThesis -
Targeting the p38 MAPK-MK2 pathway for glioblastoma therapy
Published 2016-08-01Glioblastoma is the most lethal and prevalent form of brain cancer. Its therapy is not only limited in its choices but also in extending life expectancies of patients. Identification of genetic aberrations driving tumour ...USyd AccessThesis