The importance of neuropeptide Y (NPY) and Y2 receptors in the regulation of bone and energy homeostasis has recently been demonstrated. However, the contributions of the other Y recep- tors are less clear. Here we show ...
Germ line or hypothalamus-specific deletion of Y2 receptors in mice results in a doubling of trabecular bone volume. However, the specific mechanism by which deletion of Y2 receptors increases bone mass has not yet been ...
Makovey, Joanna; Naganathan, Vasi; Seibel, Markus; Sambrook, Philip
Backgrond Ghrelin, a peptide hormone that plays a role in the regulation of appetite and body adiposity, may also play a role in bone metabolism. Objectives We used the opposite-sex twin model to study associations of ...
Makovey, Joanna; Nguyen, Tuan V; Naganathan, Vasi; Wark, John D; Sambrook, Philip
This longitudinal twin study was designed to assess the heritability of bone loss in peri- and postmenopausal women. A sample of 724 female twins was studied. Baseline and repeat BMD measurements were performed. Results ...
Vajdic, Claire M.; van Leeuwen, Marina T.; McDonald, Stephen P.; McCredie, Margaret R. E.; Law, Matthew; Chapman, Jeremy R.; Webster, Angela C.; Kaldor, John M.; Grulich, Andrew E.
Squamous cell carcinoma (SCC) of the eye occurs at substantially increased rates in individuals with human immunodeficiency virus (HIV) infection, but it has not been reported in individuals with iatrogenic or congenital ...
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