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  • EFFECTS OF INTENSIVE DIET AND EXERCISE ON KNEE JOINT LOADS, INFLAMMATION, AND CLINICAL OUTCOMES AMONG OVERWEIGHT AND OBESE ADULTS WITH KNEE OSTEOARTHRITIS 

    Messier, Stephen P; Mihalko, Shannon L; Legault, Claudine; Miller, Gary D.; Nicklas, Barbara J.; DeVita, Paul; Beavers, Daniel P; Hunter, David J.; Lyles, Mary F.; Eckstein, Felix; Williamson, Jeff D; Carr, J. Jeffery; Guermazi, Ali; Loeser, Richard F. (The Journal of the American Medical Association, 2013)
    Importance Knee osteoarthritis (OA), a common cause of chronic pain and disability, has biomechanical and inflammatory origins and is exacerbated by obesity. Objective To determine whether a ≥10% reduction in body ...
  • A Randomized Trial of Realignment Therapy for Treatment of Medial Tibiofemoral Osteoarthritis 

    Hunter, David J.; Gross, K. Douglas; McCree, Paula; Li, Ling; Hirko, Kelly; Harvey, William F (Elsevier, 2009-09)
    Objectives: The objective of this 30-week randomized crossover trial was to determine whether a multi-modal realignment therapy would be successful in relieving pain and improving function among persons with medial ...
  • THE RELATIONSHIP OF TIBIAL BONE PERFUSION TO PAIN IN KNEE OSTEOARTHRITIS. 

    Seah, S; Wheaton, D; Li, Ling; Dyke, J P; Talmo, C; Harvey, William F; Hunter, David J. (Elsevier, 2012-12)
    Objective To confirm altered perfusion within tibial bone marrow lesions (BMLs) and improve our understanding on the relationship between BMLs and pain in knee osteoarthritis (OA). Methods Participants with moderate ...
  • The MeTeOR Trial (Meniscal Tear in Osteoarthritis Research): Rationale and design features 

    Katz, Jeffrey N.; Chaisson, Christine E; Cole, Brian; Guermazi, Ali; Hunter, David J.; Jones, Morgan; Levy, Bruce A; Mandi, Lisa A; Martin, Scott; Marx, Robert G; Safran-Norton, Clare; Roemer, Frank W.; Skoniecki, Debra; Solomon, Daniel H.; Spindler, Kurt P.; Wright, John; Wright, Rick W; Losina, Elena (Elsevier, 2012-11)
    This paper presents the rationale and design features of the MeTeOR Trial (Meniscal Tear in Osteoarthritis Research; Clinical Trials.gov NCT00597012). MeTeOR is an NIH-funded seven-center prospective randomized controlled ...
  • Pattern of joint damage in persons with knee osteoarthritis and concomitant ACL tears. 

    Stein, Verena; Li, Ling; Guermazi, Ali; Zhang, Yuqing; Kwoh, C. Kent; Eaton, Charles B; Hunter, David J. (Springer, 2012-02)
    OBJECTIVE: The aim of this study was to evaluate the morphological changes of the lateral meniscus in end-stage lateral compartment osteoarthritis (OA) of the knee. METHODS: One hundred fifty-eight knee joints from 133 ...

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