• Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding 

      Lu, Roujian; Zhao, Xiang; Li, Juan; Niu, Peihua; Yang, Bo; Wu, Honglong; Wang, Wenling; Song, Hao; Huang, Baoying; Zhu, Na; Bi, Yuhai; Ma, Xuejun; Zhan, Faxian; Wang, Liang; Hu, Tao; Zhou, Hong; Hu, Zhenhong; Zhou, Weimin; Zhao, Li; Chen, Jing; Meng, Yao; Wang, Ji; Lin, Yang; Yuan, Jianying; Xie, Zhihao; Ma, Jinmin; Liu, William J.; Wang, Dayan; Xu, Wenbo; Holmes, Edward C.; Gao, George F.; Wu, Guizhen; Chen, Weijun; Shi, Weifeng; Tan, Wenjie
      Published 2020-01-01
      The ten genome sequences of 2019-nCoV obtained from the nine patients were extremely similar, exhibiting more than 99·98% sequence identity. Notably, 2019-nCoV was closely related (with 88% identity) to two bat-derived ...
      Article
    • Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding 

      Lu, Roujian; Zhao, Xiang; Li, Juan; Niu, Peihua; Yang, Bo; Wu, Honglong; Wang, Wenling; Song, Hao; Huang, Baoying; Zhu, Na; Bi, Yuhai; Ma, Xuejun; Zhan, Faxian; Wang, Liang; Hu, Tao; Zhou, Hong; Hu, Zhenhong; Zhou, Weimin; Zhao, Li; Chen, Jing; Meng, Yao; Wang, Ji; Lin, Yang; Yuan, Jianying; Xie, Zhihao; Ma, Jinmin; Liu, William J; Wang, Dayan; Xu, Wenbo; Holmes, Edward C; Gao, George F; Wu, Guizhen; Chen, Weijun; Shi, Weifeng; Tan, Wenjie
      Published 2020
      Background: In late December, 2019, patients presenting with viral pneumonia due to an unidentified microbial agent were reported in Wuhan, China. A novel coronavirus was subsequently identified as the causative pathogen, ...
      Article
    • A Genomic Perspective on the Origin and Emergence of SARS-CoV-2 

      Zhang, Y. Z.; Holmes, E. C.
      Published 2020-01-01
      The ongoing pandemic of a new human coronavirus, SARS-CoV-2, has generated enormous global concern. We and others in China were involved in the initial genome sequencing of the virus. Herein, we describe what genomic data ...
      Article
    • Global commercial passenger airlines and travel health information regarding infection control and the prevention of infectious disease: What's in a website? 

      Shaban, Ramon Z.; Sotomayor-Castillo, Cristina F.; Malik, Jeremy; Li, Cecilia
      Published 2020-01-01
      Background: Air travel has never been easier, cheaper or faster, with large volumes of people travelling around the world. These factors increase the risk of the spread of infectious diseases by air travel. Little is known, ...
      Article
    • Global coordination on cross-border travel and trade measures crucial to COVID-19 response 

      Lee, Kelley; Worsnop, Catherine Z; Grépin, Karen A; Kamradt-Scott, Adam
      Published 2020-01-01
      When WHO declared the COVID-19 outbreak a Public Health Emergency of International Concern (PHEIC) on Jan 30, 2020, under the provisions of the International Health Regulations (2005) (IHR), it recommended against “any ...
      Article
    • Global Issues of Radiopharmaceutical Access and Availability: a Nuclear Medicine Global Initiative Project. 

      Cutler, Cathy S; Bailey, Elizabeth A; Kumar, Vijay; Schwarz, Sally W; Bom, Henry Hee-Seung; Hatazawa, Jun; Paez, Diana; Orellana, Pilar; Louw, Lizette; Mut, Fernando; Kato, Hiroki; Chiti, Arturo; Frangos, Savvas; Fahey, Frederic H; Dillehay, Gary; Oh, Seoung Jun; Lee, Dong Soo; Lee, Sze Ting; Nunez-Miller, Rodolfo; Bandopadhyaya, Guru Pad; Pradhan, Prasanta; Scott, Andrew M
      Published 2020-01-01
      The Nuclear Medicine Global Initiative (NMGI) was formed in 2012 by 13 international organizations to promote human health by advancing the field of nuclear medicine and molecular imaging by supporting the practice and ...
      Article
    • Glycemic Index and Pregnancy: A Systematic Literature Review 

      Louie, Jimmy CY; Brand-Miller, JC; Markovic, TP; Ross, GP; Moses, RG
      Published 2010-01-01
      Background/Aim. Dietary glycemic index (GI) has received considerable research interest over the past 25 years although its application to pregnancy outcomes is more recent. This paper critically evaluates the current ...
      Open Access
      Article
    • Glycyrrhizic Acid Can Attenuate Metabolic Deviations Caused by a High-Sucrose Diet without Causing Water Retention in Male Sprague-Dawley Rats 

      Fernando, HA; Chandramouli, C; Rosli, D; Lam, YL; Yong, ST; Yaw, HP; Ton, SH; Kadir, K; Sainsbury, Amanda
      Published 2014-11-01
      Glycyrrhizic acid (GA) ameliorates many components of the metabolic syndrome, but its potential therapeutic use is marred by edema caused by inhibition of renal 11β-hydroxysteroid dehydrogenase 2 (11β-HSD2). We assessed ...
      Open Access
      Article
    • Goals for living with a chronic condition: The relevance of temporalities, dispositions, and resources 

      Franklin, M; Lewis, S; Willis, K; Rogers, A; Venville, A; Smith, L
      Published 2019-05-19
      Introduction: Premised on the idea that setting goals motivates action and allocation of resources toward a desired future state, goal-setting has become a key component of self-management support. ...
      Open Access
      Article
    • Greater Bone Formation of Y2 Knockout Mice Is Associated with Increased Osteoprogenitor Numbers and Altered Y1 Receptor Expression 

      Lundberg, PA; Allison, SJ; Lee, NJ; Baldock, PA; Brouard, NJ; Rost, S; Enriquez, RF; Sainsbury, Amanda; Lamghari, M; Simmons, P; Eisman, JA; Gardiner, EM; Herzog, H
      Published 2007-10-01
      Germ line or hypothalamus-specific deletion of Y2 receptors in mice results in a doubling of trabecular bone volume. However, the specific mechanism by which deletion of Y2 receptors increases bone mass has not yet been ...
      Open Access
      Article
    • Haemorrhagic bronchial casts causing complete ventilatory failure in a COVID?19 patient on ECMO 

      Herath, Samantha; Kruit, Natalie; Eslick, Adam; Giroy, Nicole
      Published 2020
      Coronavirus disease 2019 (COVID?19) was identified as causing an unusual pneumonia in Wuhan in late 2019 and rapidly evolved to a pandemic. We present a case of an otherwise well 55?year?old female patient who had seemingly ...
      Article
    • Handbook for Aboriginal Alcohol and Drug Work 

      Lee, Kylie; Freeburn, Bradley; Ella, Steve; Miller, Warren; Perry, Jimmy; Conigrave, Kate
      Published 2012-01-01
      The Handbook for Aboriginal Alcohol and Drug Work is a practical tool written for Aboriginal drug and alcohol workers, mental health workers and others working in this field. It offers a detailed look at alcohol and drug ...
      Open Access
      Book
    • The harms of smoking and benefits of smoking cessation in women compared with men with type 2 diabetes: An observational analysis of the ADVANCE (Action in Diabetes and Vascular Disease: Preterax and Diamicron modified release Controlled Evaluation) trial 

      Blomster, JI; Woodward, M; Zoungas, S; Hillis, GS; Harrap, S; Neal, B; Poulter, N; Mancia, G; Chalmers, J; Huxley, R
      Published 2016-01-01
      Objectives: In general populations, the adverse effects of smoking on coronary risk have been demonstrated to be greater in women than in men; whether this is true for individuals with diabetes is unclear. Design: Cohort ...
      Open Access
      Article
    • Healthcare Workers Bioresource: Study outline and baseline characteristics of a prospective healthcare worker cohort to study immune protection and pathogenesis in COVID-19 

      Augusto, Jo�o B; Menacho, Katia; Andiapen, Mervyn; Bowles, Ruth; Burton, Maudrian; Welch, Sophie; Bhuva, Anish N; Seraphim, Andreas; Pade, Corinna; Joy, George; Jensen, Melanie; Davies, Rhodri H; Captur, Gabriella; Fontana, Marianna; Montgomery, Hugh; O�Brien, Ben; Hingorani, Aroon D; Cutino-Moguel, Teresa; McKnight, �ine; Abbass, Hakam; Alfarih, Mashael; Alldis, Zoe; Baca, Georgina L; Boulter, Alex; Bracken, Olivia V; Bullock, Natalie; Champion, Nicola; Chan, Carmen; Couto-Parada, Xose; Dieobi-Anene, Keenan; Feehan, Karen; Figtree, Gemma; Figtree, Melanie C; Finlay, Malcolm; Forooghi, Nasim; Gibbons, Joseph M; Griffiths, Peter; Hamblin, Matt; Howes, Lee; Itua, Ivie; Jones, Meleri; Jardim, Victor; Kapil, Vikas; Lee, Wing-Yiu Jason; Mandadapu, Vineela; Mfuko, Celina; Mitchelmore, Oliver; Palma, Susana; Patel, Kush; Petersen, Steffen E; Piniera, Brian; Raine, Rosalind; Rapala, Alicja; Richards, Amy; Sambile, Genine; de Sousa, Jorge Couto; Sugimoto, Michelle; Thornton, George D; Artico, Jessica; Zahedi, Dan; Parker, Ruth; Robathan, Mathew; Hickling, Lauren M; Ntusi, Ntobeko; Semper, Amanda; Brooks, Tim; Jones, Jessica; Tucker, Art; Veerapen, Jessry; Vijayakumar, Mohit; Wodehouse, Theresa; Wynne, Lucinda; Treibel, Thomas A; Noursadeghi, Mahdad; Manisty, Charlotte; Moon, James C
      Published 2020
      Background: Most biomedical research has focused on sampling COVID-19 patients presenting to hospital with advanced disease, with less focus on the asymptomatic or paucisymptomatic. We established a bioresource with serial ...
      Article
    • Heart failure care in low- and middle-income countries: a systematic review and meta-analysis 

      Callender, T; Woodward, M; Roth, G; Farzadfar, F; Lemarie, JC; Gicquel, S; Atherton, J; Rahimzadeh, S; Ghaziani, M; Shaikh, M; Bennett, D; Patel, A; Lam, CSP; Sliwa, K; Barretto, A; Siswanto, BB; Diaz, A; Herpin, D; Krum, H; Eliasz, T; Forbes, A; Kiszely, A; Khosla, R; Petrinic, T; Praveen, D; Shrivastava, R; Xin, D; McMahon, S; McMurray, J; Rahimi, K
      Published 2014-08-12
      Background: Heart failure places a significant burden on patients and health systems in high-income countries. However, information about its burden in low- and middle-income countries (LMICs) is scant. We thus set out to ...
      Open Access
      Article
    • Hepatitis C Virus Driven AXL Expression Suppresses the Hepatic Type I Interferon Response 

      Read, Scott A; Tay, Enoch; Shahidi, Mahsa; O'Connor, Kate; Booth, David; George, Jacob; Douglas, Mark
      Published 2015-01-01
      Treatment of chronic hepatitis C virus (HCV) infection is evolving rapidly with the development of novel direct acting antivirals (DAAs), however viral clearance remains intimately linked to the hepatic innate immune system. ...
      Open Access
      Article
    • Hepatitis C Virus Induces the Cannabinoid Receptor 1 

      van der Poorten, David; Shahidi, Mahsa; Tay, Enoch; Sesha, Jayshree; Tran, Kayla; McLeod, Duncan; Milliken, J; Ho, Vicki; Hebbard, Lionel; Douglas, Mark; George, Jacob
      Published 2010-01-01
      Background: Activation of hepatic CB1 receptors (CB1) is associated with steatosis and fibrosis in experimental forms of liver disease. However, CB1 expression has not been assessed in patients with chronic hepatitis C ...
      Open Access
      Article
    • Hepatitis transmission risk IN kidney Transplantation (the HINT study); a cross-sectional survey of transplant clinicians in Australian and New Zealand 

      Waller, Karen M.J.; Wyburn, Kate R.; Shackel, Nicholas A.; O’Leary, Michael J.; Kelly, Patrick J.; Webster, Angela C
      Published 2018-01-01
      Background Interpreting hepatitis serology and virus transmission risk in transplantation can be challenging. Decisions must balance opportunity to transplant against potential infection transmission. We aimed to survey ...
      Open Access
      Article
    • High content analysis of granuloma histology and neutrophilic inflammation in adult zebrafish infected with Mycobacterium marinum 

      Cheng, Tina; Kam, Julia; Johansen, Matt; Oehlers, Stefan
      Published 2020-02-01
      Infection of zebrafish with natural pathogen Mycobacterium marinum is a useful surrogate for studying the human granulomatous inflammatory response to infection by Mycobacterium tuberculosis. The adaptive immune system of ...
      Embargoed
      Article
    • High osteoporotic fracture risk and CVD risk co-exist in postmenopausal women 

      Makovey, Joanna; Macara, Monique; Chen, Jian Sheng; Hayward, Christopher; March, Lyn; Sambrook, Philip
      Published 2013-01-01
      Introduction: Osteoporosis related risk factors such as BMD have been associated with cardiovascular endpoints in previous studies but there have been no studies of integrated risk using risk factor algorithms. Methods: A ...
      Open Access
      Article