Tumour imaging using hCG-specific monoclonal antibodies

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Open Access

Field	Value	Language
dc.contributor.author	Yeates, Peter Gregory
dc.date.accessioned	2021-09-22T23:33:28Z
dc.date.available	2021-09-22T23:33:28Z
dc.date.issued	1989	en_AU
dc.identifier.uri	https://hdl.handle.net/2123/26188
dc.description	991024486289705016_v1	en_AU
dc.description.abstract	The aim of this thesis was to radiolabel two different anti-hCG antibodies with 111-indium, and to determine their specific tumour uptake and tissue biodistribution into choriocarcinoma xenografts in nude mice against 111-indium and 67-gallium citrate over 72 hours. Comparative radioimmunoscintigraphy was performed to determine the optimal imaging post injection for visualisation of tumour sites. Data manipulation using dual isotope computerised subtraction in mouse phantom models was evaluated as means of improving tumour delineation in low tumour contrast studies.	en_AU
dc.language.iso	en	en_AU
dc.subject	Monoclonal antibodies	en_AU
dc.subject	imaging systems in medicine	en_AU
dc.subject	Tumors -- Diagnosis	en_AU
dc.title	Tumour imaging using hCG-specific monoclonal antibodies	en_AU
dc.type	Thesis
dc.type.thesis	Masters by Research	en_AU
dc.rights.other	The author retains copyright of this thesis. It may only be used for the purposes of research and study. It must not be used for any other purposes and may not be transmitted or shared with others without prior permission.	en_AU
usyd.faculty	Faculty of Science	en_AU
usyd.degree	Master of Pharmacy M.Pharm.	en_AU
usyd.awardinginst	The University of Sydney	en_AU