• Open-field PET: Simultaneous brain functional imaging and behavioural response measurements in freely moving small animals 

      Kyme, Andre; Angelis, Georgios I.; Eisenhuth, John; Fulton, Roger R.; Zhou, Victor; Hart, Genevra; Popovic, Kata; Akhtar, Mahmood; Ryder, William J.; Clemens, Kelly J.; Balleine, Bernard W.; Parmar, Arvind; Pascali, Giancarlo; Perkins, Gary; Meikle, Steven R.
      Published 2019
      A comprehensive understanding of how the brain responds to a changing environment requires techniques capable of recording functional outputs at the whole-brain level in response to external stimuli. Positron emission tomography ...
      Open Access
      Article
    • Optical imaging spectroscopy for rapid, primary screening of SARS-CoV-2: a proof of concept 

      Gomez-Gonzalez, Emilio; Barriga-Rivera, Alejandro; Fernandez-Muñoz, Beatriz; Navas-Garcia, Jose Manuel; Fernandez-Lizaranzu, Isabel; Munoz-Gonzalez, Francisco Javier; Parrilla-Giraldez, Ruben; Requena-Lancharro, Desiree; Gil-Gamboa, Pedro; Rosell-Valle, Cristina; Gomez-Gonzalez, Carmen; Mayorga-Buiza, Maria Jose; Martin-Lopez, Maria; Muñoz, Olga; Gomez-Martin, Juan Carlos; Relimpio-Lopez, Maria Isabel; Aceituno-Castro, Jesus; Perales-Esteve, Manuel A.; Puppo-Moreno, Antonio; Garcia-Cozar, Francisco Jose; Olvera-Collantes, Lucia; Gomez-Diaz, Raquel; de los Santos-Trigo, Silvia; Huguet-Carrasco, Monserrat; Rey, Manuel; Gomez, Emilia; Sanchez-Pernaute, Rosario; Padillo-Ruiz, Javier; Marquez-Rivas, Javier
      Published 2022
      Effective testing is essential to control the coronavirus disease 2019 (COVID-19) transmission. Here we report a-proof-of-concept study on hyperspectral image analysis in the visible and near-infrared range for primary ...
      Article
    • An optimized feature detector for markerless motion tracking in motion-compensated neuroimaging 

      Henry, David; Yao, Yidi; Fulton, Roger R.; Kyme, Andre
      Published 2017
      Head movements during PET and MRI scans can have a detrimental effect on image quality and quantitative measurements. For both modalities, motion correction methods exist that rely on accurate characterization of head ...
      Open Access
      Conference paper
    • Platelet Mechanobiology Inspired Microdevices: From Hematological Function Tests to Disease and Drug Screening 

      Zhang, Yingqi; Jiang, Fengtao; Chen, Yunfeng; Ju, Lining Arnold
      Published 2022
      Platelet function tests are essential to profile platelet dysfunction and dysregulation in hemostasis and thrombosis. Clinically they provide critical guidance to the patient management and therapeutic evaluation. Recently, ...
      Article
    • Silhouette-based markerless motion estimation of awake rodents in PET 

      Kyme, Andre; Strenge, Paul; Lee, Felicity; Meikle, Steven
      Published 2017
      The ability to image the brain of a freely moving rodent using motion-compensated PET presents many exciting possibilities for exploring the links between brain function and behavior. Markerless optical approaches for pose ...
      Open Access
      Conference paper