Recent Submissions

  • Syntheses and reductions of C-dimesitylboryl-1,2-dicarba-closo-dodecaboranes 

    Kahlert, Jan; Böhling, Lena; Brockhinke, Andreas; Stammler, Hans-Georg; Neumann, Beate; Rendina, Louis M.; Low, Paul J.; Weber, Lothar; Fox, Mark A. (Royal Society of Chemistry, 2015-04-24)
    Two C-dimesitylboryl-1,2-dicarba-closo-dodecaboranes, 1-(BMes2)-2-R-1,2-C2B10H10 (1, R = H, 2, R = Ph), were synthesised by lithiation of 1,2-dicarba-closo-dodecaborane and 1-phenyl-1,2-dicarba-closo-dodecaborane, respectively, ...
  • The first indoleamine-2,3-dioxygenase-1 (IDO1) inhibitors containing carborane 

    Austin, Christopher J. D.; Kahlert, Jan; Issa, Fatiah; Reed, John H.; Smith, Jason R.; Ioppolo, Joseph A.; Ong, Jennifer A.; Jamie, Joanne F.; Hibbs, David; Rendina, Louis M. (Royal Society of Chemistry, 2014-04-22)
    Indoleamine-2,3-dioxygenase-1 (IDO1) is a critical immunoregulatory enzyme responsible for the metabolism of tryptophan during inflammation and disease. Based upon a pyranonaphthoquinone framework, the first examples of ...
  • Site-specific synthesis of a hybrid boron-graphene salt 

    Kahlert, Jan U.; Austin, Christopher J. D.; Hall, Andrew J.; Rawal, Aditya; Hook, James M.; Rendina, Louis M.; Choucair, Mohammad (Royal Society of Chemistry, 2016)
    We report the first example of an ionic graphene salt containing boron. An anionic charge is introduced to the graphene surface by means of 7,8-nido-[C2B9H11]− carborane clusters covalently and electronically bound to the ...
  • Efficient radiosynthesis of a [18F]-phosphonium salt containing closo-carborane 

    Ioppolo, Joseph A.; Giboureau, Nicolas; Bhadbhade, Mohan; Morrison, Daniel E.; Kassiou, Michael; Rendina, Louis M. (Elsevier, 2017-11-15)
    An efficient synthesis of an 18F-labelled phosphonium salt containing closo-carborane is described. The preparation of this salt was attempted using both single-step and two-step protocols, with greater success found for ...
  • Molecular Recognition of an Adenine Derivative by Organoplatinum(II) Complexes with Hydrogen-Bonding Functionality 

    Crisp, Michael G.; Kavianpour, Poya; Rendina, Louis M. (Elsevier, 2019-03-15)
    The first examples of adenine binding by isomeric organoplatinum(II) complexes bearing H-bonding nicotinic and isonicotinic acid ligands are reported. Notably, a subtle switching of the H-bonding functionality from the 3- ...

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