Browsing Research Publications and Outputs by subject "1115 Pharmacology and Pharmaceutical Sciences"
Sort by:
Title A-Z
-
The effect of charge on the uptake and resistance to reduction of platinum(IV) complexes in human serum and whole blood models
Hambley, Trevor; Chen, Catherine; Gui, Xiao; Kappen, Peter; Renfrew, AnnaPublished 2020cis- and trans-Platinum(IV) complexes with diaminetetracarboxylate coordination spheres possess the highly desirable property of exhibiting unusual resistance to reduction by blood serum components and endogenous reductants ...Open AccessArticle -
The impact of highly electron withdrawing carboxylato ligands on the stability and activity of platinum(IV) pro-drugs
Hambley, Trevor; Chen, CatherinePublished 2019Recent developments in the design of platinum(IV) pro-drug candidates have demonstrated the importance of the coordination sphere of the complex in determining the resistance to reduction by endogenous reductants and the ...Open AccessArticle
Sort by:
Title A-Z