|dc.identifier.citation||Int J Radiat Oncol Biol Phys. 2016 Mar 1;94(3):628-36.||en_AU|
|dc.description.abstract||PURPOSE: To assess the impact of an audiovisual (AV) biofeedback on intra- and
interfraction tumor motion for lung cancer patients.
METHODS AND MATERIALS: Lung tumor motion was investigated in 9 lung cancer
patients who underwent a breathing training session with AV biofeedback before 2
3T magnetic resonance imaging (MRI) sessions. The breathing training session was
performed to allow patients to become familiar with AV biofeedback, which uses a
guiding wave customized for each patient according to a reference breathing
pattern. In the first MRI session (pretreatment), 2-dimensional cine-MR images
with (1) free breathing (FB) and (2) AV biofeedback were obtained, and the second
MRI session was repeated within 3-6 weeks (mid-treatment). Lung tumors were
directly measured from cine-MR images using an auto-segmentation technique; the
centroid and outlier motions of the lung tumors were measured from the segmented
tumors. Free breathing and AV biofeedback were compared using several metrics:
intra- and interfraction tumor motion consistency in displacement and period, and
the outlier motion ratio.
RESULTS: Compared with FB, AV biofeedback improved intrafraction tumor motion
consistency by 34% in displacement (P=.019) and by 73% in period (P<.001).
Compared with FB, AV biofeedback improved interfraction tumor motion consistency
by 42% in displacement (P<.046) and by 74% in period (P=.005). Compared with FB,
AV biofeedback reduced the outlier motion ratio by 21% (P<.001).
CONCLUSIONS: These results demonstrated that AV biofeedback significantly
improved intra- and interfraction lung tumor motion consistency for lung cancer
patients. These results demonstrate that AV biofeedback can facilitate consistent
tumor motion, which is advantageous toward achieving more accurate medical
imaging and radiation therapy procedures.||en_AU|
|dc.relation||NHMRC 633000; NHMRC 1112096||en_AU|
|dc.title||Audiovisual Biofeedback Improves Cine-Magnetic Resonance Imaging Measured Lung Tumor Motion Consistency.||en_AU|
|dc.description.addcoll||Sydney Medical School Research Papers and Publications||en_AU|
|Appears in Collections:||Research Papers and Publications. Sydney Medical School|