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|Title: ||Tissue biomarkers detected by immunohistochemistry as diagnostic and prognostic indicators in human malignancies|
|Authors: ||Andrici, Juliana|
|Issue Date: ||15-Sep-2016|
|Publisher: ||University of Sydney|
Sydney Medical School
|Abstract: ||Immunohistochemistry involves the use of labelled antobodies to detect and visualise the presence of selected antigens. It is widely used in the doagnosis of cancers in which specific antigens are either up-regulated or absent.«br /» We are studying newly-discovered biomarkers such as BAP1, and are suggesting novel uses for them in the diagnosis of cancers such as malignant mesothelioma, cholangiocarcinoma, and gynecological malignancies.«br /» We are also examining the role of microsatellite instability in the diagnosis of colorectal cancer and adrenocortical cancer.|
|Access Level: ||Access is restricted to staff and students of the University of Sydney . UniKey credentials are required. Non university access may be obtained by visiting the University of Sydney Library.|
|Rights and Permissions: ||The author retains copyright of this thesis. It may only be used for the purposes of research and study. It must not be used for any other purposes and may not be transmitted or shared with others without prior permission.|
|Type of Work: ||PhD Doctorate|
|Type of Publication: ||Doctor of Philosophy Ph.D.|
|Appears in Collections:||Sydney Digital Theses (University of Sydney Access only)|
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|Andrici_J_Final Thesis.pdf||Thesis||7.57 MB||Adobe PDF|
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