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|Title: ||Meta-analyses of early versus delayed laparoscopic cholecystectomy for acute cholecystitis: pooled analyses comparing timing and single incision laparoscopic cholecystectomy|
|Authors: ||Cao, Amy M Y|
|Keywords: ||Keywords: laparoscopic cholecystectomy meta-analyses|
|Issue Date: ||26-Oct-2016|
|Publisher: ||University of Sydney|
Medicine (Sydney Medical School)
|Abstract: ||Meta-analyses of early versus delayed laparoscopic cholecystectomy for acute cholecystitis: pooled analyses comparing timing and single incision laparoscopic cholecystectomy
Laparoscopic cholecystectomy is well established as the gold standard treatment for biliary colic. Historically laparoscopic cholecystectomy was contra-indicated in acute cholecystitis in the early 1990s for fear of increased complications, more notably fear of increased biliary injuries. However with improving surgical technique and familiarity with laparoscopic cholecystectomy, it is now indicated in acute cholecystitis. The timing of laparoscopic cholecystectomy in acute cholecystitits however continues to be a source of ongoing debate with some surgeons continuing to advocate delayed surgery up to 6-8 weeks after the initial admission for acute cholecystitis whilst others believing early surgery can provide safer and improved patient outcomes. In addition, the definition of early surgery varies significantly from within 24 hours to seven days of admission or onset of symptoms. Furthermore, with improving laparoscopic skills in cholecystectomy, there have been increased innovations to improve the current laparoscopic cholecystectomy. Single incision laparoscopic cholecystectomy is one such innovation being researched with much enthusiasm.
The aim of this thesis is to undertake meta-analyses on the current literature to provide evidence on early versus delayed laparoscopic cholecystectomy in acute cholecystitis investigating data from randomised controlled trials and case control studies as well as undertake a meta-analysis on single versus multi-port laparoscopic cholecystectomy. A review of surgical techniques in laparoscopic cholecystectomy and methodological techniques in meta-analyses and the role of case control studies will also be undertaken.|
|Access Level: ||Access is restricted to staff and students of the University of Sydney . UniKey credentials are required. Non university access may be obtained by visiting the University of Sydney Library.|
|Rights and Permissions: ||The author retains copyright of this thesis. It may only be used for the purposes of research and study. It must not be used for any other purposes and may not be transmitted or shared with others without prior permission.|
|Type of Work: ||Masters Thesis|
|Type of Publication: ||Master of Surgery M.S.|
|Appears in Collections:||Sydney Digital Theses (University of Sydney Access only)|
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|CAO, Amy - Final Copy Thesis.pdf||CAO, Amy - Final Copy Thesis||2.64 MB||Adobe PDF|
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