Browsing by author "Poulsen, PR"
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Determining appropriate imaging parameters for kilovoltage intrafraction monitoring: an experimental phantom study.
Wallace, D; Ng, JA; Keall, P; O'Brien, RT; Poulsen, PR; Juneja, P; Booth, JTPublished 2015-06-01Kilovoltage intrafraction monitoring (KIM) utilises the kV imager during treatment for real-time tracking of prostate fiducial markers. However, its effectiveness relies on sufficient image quality for the fiducial tracking ...Open AccessArticle -
Electromagnetic-Guided MLC Tracking Radiation Therapy for Prostate Cancer Patients: Prospective Clinical Trial Results.
Keall, P; Colvill, E; O'Brien, R; Caillet, V; Eade, T; Kneebone, A; Hruby, G; Poulsen, PR; Zwan, B; Greer, PB; Booth, JPublished 2018-06-01PURPOSE: To report on the primary and secondary outcomes of a prospective clinical trial of electromagnetic-guided multileaf collimator (MLC) tracking radiation therapy for prostate cancer. METHODS AND MATERIALS: Twenty-eight ...Open AccessArticle -
Fast motion-including dose error reconstruction for VMAT with and without MLC tracking
Rakvilde, T; Keall, P; Grau, C; Høyer, M; Poulsen, PRPublished 2014-12-01Multileaf collimator (MLC) tracking is a promising and clinically emerging treatment modality for radiotherapy of mobile tumours. Still, new quality assurance (QA) methods are warranted to safely introduce MLC tracking in ...Open AccessArticle -
The first clinical implementation of a real-time six degree of freedom target tracking system during radiation therapy based on Kilovoltage Intrafraction Monitoring (KIM).
Nguyen, DT; O'Brien, R; Kim, JH; Huang, CY; Wilton, L; Greer, P; Legge, K; Booth, JT; Poulsen, PR; Martin, J; Keall, PPublished 2017-04-01PURPOSE: We present the first clinical implementation of a real-time six-degree of freedom (6DoF) Kilovoltage Intrafraction Monitoring (KIM) system which tracks the cancer target translational and rotational motions during ...Open AccessArticle -
The first clinical implementation of real-time image-guided adaptive radiotherapy using a standard linear accelerator.
Keall, P; Nguyen, DT; O'Brien, R; Caillet, V; Hewson, E; Poulsen, PR; Bromley, R; Bell, L; Eade, T; Kneebone, A; Martin, J; Booth, JTPublished 2018-04-01PURPOSE: Until now, real-time image guided adaptive radiation therapy (IGART) has been the domain of dedicated cancer radiotherapy systems. The purpose of this study was to clinically implement and investigate real-time ...Open AccessArticle -
In Reply to Dahele and Verbakel
Keall, P; Nguyen, DT; O'Brien, RT; Zhang, P; Bertholet, J; Poulsen, PRPublished 2019-01-01N/AOpen AccessArticle, Letter -
An interdimensional correlation framework for real-time estimation of six degree of freedom target motion using a single x-ray imager during radiotherapy.
Nguyen, DT; Bertholet, J; Kim, JH; O'Brien, R; Booth, JT; Poulsen, PR; Keall, PPublished 2017-12-01Increasing evidence suggests that intrafraction tumour motion monitoring needs to include both 3D translations and 3D rotations. Presently, methods to estimate the rotation motion require the 3D translation of the target ...Open AccessArticle -
Investigating multi-leaf collimator tracking in stereotactic arrhythmic radioablation (STAR) treatments for atrial fibrillation.
Lydiard, S; Caillet, V; Ipsen, S; O'Brien, R; Blanck, O; Poulsen, PR; Booth, J; Keall, PPublished 2018-09-01Stereotactic arrhythmia radioablation (STAR) is an emerging treatment option for atrial fibrillation (AF). However, it faces possibly the most challenging motion compensation scenario: both respiratory and cardiac motion. ...Open AccessArticle -
Multileaf Collimator Tracking Improves Dose Delivery for Prostate Cancer Radiation Therapy: Results of the First Clinical Trial.
Colvill, E; Booth, JT; O'Brien, RT; Eade, TN; Kneebone, AB; Poulsen, PR; Keall, PPublished 2015-08-01PURPOSE: To test the hypothesis that multileaf collimator (MLC) tracking improves the consistency between the planned and delivered dose compared with the dose without MLC tracking, in the setting of a prostate cancer ...Open AccessArticle -
Potential improvements of lung and prostate MLC tracking investigated by treatment simulations.
Toftegaard, J; Keall, P; O'Brien, R; Ruan, D; Ernst, F; Homma, N; Ichiji, K; Poulsen, PRPublished 2018-05-01PURPOSE/OBJECTIVES: Intrafraction tumor motion during external radiotherapy is a challenge for the treatment accuracy. A novel technique to mitigate the impact of tumor motion is real-time adaptation of the multileaf ...Open AccessArticle -
Quality assurance for the clinical implementation of kilovoltage intrafraction monitoring for prostate cancer VMAT.
Ng, J; Booth, JT; O'Brien, RT; Colvill, E; Huang, CY; Poulsen, PR; Keall, PPublished 2014-11-01PURPOSE: Kilovoltage intrafraction monitoring (KIM) is a real-time 3D tumor monitoring system for cancer radiotherapy. KIM uses the commonly available gantry-mounted x-ray imager as input, making this method potentially ...Open AccessArticle -
Real-Time 3D Image Guidance Using a Standard LINAC: Measured Motion, Accuracy, and Precision of the First Prospective Clinical Trial of Kilovoltage Intrafraction Monitoring-Guided Gating for Prostate Cancer Radiation Therapy.
Keall, P; Ng, JA; Juneja, P; O'Brien, RT; Huang, CY; Colvill, E; Caillet, V; Simpson, E; Poulsen, PR; Kneebone, A; Eade, T; Booth, JTPublished 2016-04-01PURPOSE: Kilovoltage intrafraction monitoring (KIM) is a new real-time 3-dimensional image guidance method. Unlike previous real-time image guidance methods, KIM uses a standard linear accelerator without any additional ...Open AccessArticle -
Review of Real-Time 3-Dimensional Image Guided Radiation Therapy on Standard-Equipped Cancer Radiation Therapy Systems: Are We at the Tipping Point for the Era of Real-Time Radiation Therapy?
Keall, P; Nguyen, DT; O'Brien, R; Zhang, P; Happersett, L; Bertholet, J; Poulsen, PRPublished 2018-11-15PURPOSE: To review real-time 3-dimensional (3D) image guided radiation therapy (IGRT) on standard-equipped cancer radiation therapy systems, focusing on clinically implemented solutions. METHODS AND MATERIALS: Three groups ...Open AccessArticle -
Time-resolved dose reconstruction by motion encoding of volumetric modulated arc therapy fields delivered with and without dynamic multi-leaf collimator tracking.
Rakvilde, T; Keall, P; Grau, C; Høyer, M; Poulsen, PRPublished 2013-10-01BACKGROUND: Organ motion during treatment delivery in radiotherapy (RT) may lead to deterioration of the planned dose, but can be mitigated by dynamic multi-leaf collimator (DMLC) tracking. The purpose of this study was ...Open AccessArticle
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