Browsing by author "Patel, A"
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Effects of the Endpoint Adjudication Process on the Results of a Randomised Controlled Trial: The ADVANCE Trial
Hata, J; Arima, H; Zoungas, S; Fulcher, G; Pollock, C; Adams, M; Watson, J; Joshi, R; Kengne, AP; Ninomiya, T; Anderson, C; Woodward, M; Patel, A; Mancia, G; Poulter, N; McMahon, S; Chalmers, J; Neal, BPublished 2013-02-04Background: Endpoint adjudication committees (EPAC) are widely used in clinical trials. The aim of the present analysis is to assess the effects of the endpoint adjudication process on the main findings of the ADVANCE trial ...Open AccessArticle -
The Efficacy and Tolerability of ‘Polypills’: Meta-Analysis of Randomised Controlled Trials
Elley, CR; Gupta, AK; Webster, R; Selak, V; Jun, M; Patel, A; Rodgers, A; Thom, SPublished 2012-12-19Background: To assess the blood pressure and lipid-lowering efficacy and tolerability of ‘polypills’ used in cardiovascular disease prevention trials. Methodology/Principal Findings: Systematic review and meta-analysis. ...Open AccessArticle -
Heart failure care in low- and middle-income countries: a systematic review and meta-analysis
Callender, T; Woodward, M; Roth, G; Farzadfar, F; Lemarie, JC; Gicquel, S; Atherton, J; Rahimzadeh, S; Ghaziani, M; Shaikh, M; Bennett, D; Patel, A; Lam, CSP; Sliwa, K; Barretto, A; Siswanto, BB; Diaz, A; Herpin, D; Krum, H; Eliasz, T; Forbes, A; Kiszely, A; Khosla, R; Petrinic, T; Praveen, D; Shrivastava, R; Xin, D; McMahon, S; McMurray, J; Rahimi, KPublished 2014-08-12Background: Heart failure places a significant burden on patients and health systems in high-income countries. However, information about its burden in low- and middle-income countries (LMICs) is scant. We thus set out to ...Open AccessArticle -
Impact of prior use of four preventive medications on outcomes in patients hospitalized for acute coronary syndrome- Results from CPACS-2 study
Li, M; Huang, Y; Du, X; Li, S; Ji, J; Patel, A; Gao, R; Wu, YPublished 2016-09-01© 2016 Li et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...Open AccessArticle -
An integrated general practice and pharmacy-based intervention to promote the use of appropriate preventive medications among individuals at high cardiovascular disease risk: Protocol for a cluster randomized controlled trial
Hayek, A; Joshi, R; Usherwood, T; Webster, R; Kaur, B; Saini, B; Armour, C; Krass, I; Laba, TL; Reid, C; Shiel, L; Hespe, C; Hersch, F; Jan, S; Lo, S; Peiris, D; Rodgers, A; Patel, APublished 2016-09-16© 2016 The Author(s). Background: Cardiovascular diseases (CVD) are responsible for significant morbidity, premature mortality, and economic burden. Despite established evidence that supports the use of preventive medications ...Open AccessArticle -
INterpreting the Processes of the UMPIRE Trial (INPUT): protocol for a qualitative process evaluation study of a fixed-dose combination (FDC) strategy to improve adherence to cardiovascular medications
Salam, A; Stewart, F; Singh, K; Thom, S; Williams, HJ; Patel, A; Jan, S; Laba, T; Prabhakaran, D; Maulik, P; Day, S; Ward, HPublished 2013-05-22Introduction: This paper describes a planned process evaluation of the Use of a Multidrug Pill In Reducing Cardiovascular Events (UMPIRE) trial, one of several randomised clinical trials taking place globally to assess the ...Open AccessArticle -
A multifaceted quality improvement intervention for CVD risk management in Australian primary healthcare: a protocol for a process evaluation
Patel, B; Patel, A; Jan, S; Usherwood, T; Harris, M; Panaretto, K; Zwar, N; Redfern, J; Jansen, J; Doust, J; Peiris, DPublished 2014-12-17Background: Cardiovascular disease (CVD) is the leading cause of death and disability worldwide. Despite the widespread availability of evidence-based clinical guidelines and validated risk predication equations for ...Open AccessArticle -
A multifaceted strategy using mobile technology to assist rural primary healthcare doctors and frontline health workers in cardiovascular disease risk management: protocol for the SMARTHealth India cluster randomised controlled trial
Praveen, D; Patel, A; MacMahon, S; Prabhakaran, D; Clifford, GD; Maulik, PK; Joshi, R; Jan, S; Heritier, S; Peiris, DPublished 2013-11-25Background: Blood Pressure related disease affected 118 million people in India in the year 2000; this figure will double by 2025. Around one in four adults in rural India have hypertension, and of those, only a minority ...Open AccessArticle -
The potential and value of epidemiology in curbing non-communicable diseases
Patel, A; Webster, RPublished 2016-03-29Non-communicable diseases (NCDs) have reached pandemic levels globally and pose a major threat to social and economic development worldwide. The discipline of epidemiology has done much to bring this issue to the forefront ...Open AccessArticle -
Pragmatic Trials for Noncommunicable Diseases: Relieving Constraints
Patel, A; Webster, RPublished 2016-03-01At the 65th World Health Assembly in 2012, all World Health Organization member states made a historic commitment to reduce premature deaths from noncommunicable diseases (NCDs, including cardiovascular diseases, diabetes, ...Open AccessArticle -
Process evaluation of the impact and acceptability of a polypill for prevention of cardiovascular disease
Wood, F; Salam, A; Singh, K; Day, S; Jan, S; Prabhakaran, D; Rodgers, A; Patel, A; Thom, S; Ward, HPublished 2015-09-30Importance: The Use of a Multidrug Pill In Reducing cardiovascular Events (UMPIRE) trial has shown improved adherence with the use of a polypill strategy when compared with usual medications for cardiovascular disease (CVD) ...Open AccessArticle -
Resting Heart Rate and the Risk of Microvascular Complications in Patients With Type 2 Diabetes Mellitus
Hillis, GS; Hata, J; Woodward, M; Perkovic, V; Arima, H; Chow, CK; Zoungas, S; Patel, A; Poulter, NR; Mancia, G; Williams, B; Chalmers, JPublished 2012-09-26Background: A higher resting heart rate is associated with an increased probability of cardiovascular complications and premature death in patients with type 2 diabetes mellitus. The impact of heart rate on the risk of ...Open AccessArticle -
Study protocol: systematic review of the burden of heart failure in low- and middle-income countries
Bennet, DA; Eliasz, TK; Forbes, A; Kiszely, A; Kholsa, R; Petrinic, T; Praveen, D; Shrivastava, R; Xin, D; Patel, A; MacMahon, S; Rahimi, KPublished 2012-11-29Background: Setting priorities for the prevention and management of heart failure requires an empirical understanding of the pattern of disease burden. We aim to describe the methods for a systematic review of the literature ...Open AccessArticle -
The systematic medical appraisal, referral and treatment (smart) mental health project: Development and testing of electronic decision support system and formative research to understand perceptions about mental health in rural India
Maulik, PK; Tewari, A; Devarapalli, S; Kallakuri, S; Patel, APublished 2016-10-01© 2016 Maulik et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original ...Open AccessArticle -
Systematic medical assessment, referral and treatment for diabetes care in China using lay family health promoters: Protocol for the SMARTDiabetes cluster randomised controlled trial
Peiris, D; Sun, L; Patel, A; Tian, M; Essue, B; Jan, S; Zhang, PPublished 2016-08-17Background: Type 2 diabetes (T2DM) affects 113.9 million people in China, the largest number of any country in the world (JAMA 310:948-59, 2013). T2DM prevalence has risen dramatically from around 1 % in the 1980s to now ...Open AccessArticle -
Task Shifting for Non-Communicable Disease Management in Low and Middle Income Countries – A Systematic Review
Joshi, R; Alim, M; Kengne, AP; Jan, S; Maulik, PK; Peiris, D; Patel, APublished 2014-08-14Background: One potential solution to limited healthcare access in low and middle income countries (LMIC) is task-shifting- the training of non-physician healthcare workers (NPHWs) to perform tasks traditionally undertaken ...Open AccessArticle -
The Treatment of cardiovascular Risk in Primary care using Electronic Decision suppOrt (TORPEDO) study: intervention development and protocol for a cluster randomised, controlled trial of an electronic decision support and quality improvement intervention in Australian primary healthcare
Peiris, D; Usherwood, T; Panaretto, K; Harris, M; Hunt, J; Patel, B; Zwar, N; Redfern, J; MacMahon, S; Colagiuri, S; Hayman, N; Patel, APublished 2012-11-19Background: Large gaps exist in the implementation of guideline recommendations for cardiovascular disease (CVD) risk management. Electronic decision support (EDS) systems are promising interventions to close these gaps ...Open AccessArticle
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