Browsing by author "Keall, P"
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4-Dimensional Cone Beam Computed Tomography-Measured Target Motion Underrepresents Actual Motion
Steiner, E; Shieh, CC; Caillet, V; Booth, J; Hardcastle, N; Briggs, A; Jayamanne, D; Haddad, C; Eade, T; Keall, PPublished 2018-11-15PURPOSE: Four-dimensional cone beam computed tomography (4DCBCT) facilitates verification of lung tumor motion before each treatment fraction and enables accurate patient setup in lung stereotactic ablative body radiation ...Open AccessArticle -
The accuracy and precision of Kilovoltage Intrafraction Monitoring (KIM) six degree-of-freedom prostate motion measurements during patient treatments.
Kim, JH; Nguyen, DT; Booth, JT; Huang, CY; Fuangrod, T; Poulsen, P; O'Brien, R; Caillet, V; Eade, T; Kneebone, A; Keall, PPublished 2018-02-01BACKGROUND AND PURPOSE: To perform a quantitative analysis of the accuracy and precision of Kilovoltage Intrafraction Monitoring (KIM) six degree-of-freedom (6DoF) prostate motion measurements during treatments. MATERIAL ...Open AccessArticle -
The Accuracy and Precision of the KIM Motion Monitoring System Used in the Multi-Institutional TROG 15.01 Stereotactic Prostate Ablative Radiotherapy With KIM (SPARK) Trial
Hewson, E; Nguyen, DT; O'Brien, R; Kim, J-H; Montanaro, T; Moodie, T; Greer, P; Hardcastle, N; Eade, T; Kneebone, A; Hruby, G; Hayden, A; Turner, S; Siva, S; Tai, K-H; Hunter, P; Sams, J; Poulsen, P; Booth, J; Martin, J; Keall, PPublished 2019-01-01Purpose: Kilovoltage intrafraction monitoring (KIM) allows for real-time image guidance for tracking tumor motion in six-degrees-of-freedom (6DoF) on a standard linear accelerator. This study assessed the geometric accuracy ...Open AccessArticle -
The adaptation and investigation of cone-beam CT reconstruction algorithms for horizontal rotation fixed-gantry scans of rabbits.
Gardner, M; Dillon, O; Shieh, C-C; O'Brien, R; Debrot, E; Barber, J; Ahern, V; Bennett, P; Heng, SM; Corde, S; Jackson, M; Keall, PPublished 2021Fixed-gantry radiation therapy has been proposed as a low-cost alternative to the conventional rotating-gantry radiation therapy, that may help meet the rising global treatment demand. Fixed-gantry systems require gravitational ...Open AccessArticle -
Adapting to the motion of multiple independent targets using multileaf collimator tracking for locally advanced prostate cancer: Proof of principle simulation study.
Hewson, E; Ge, Y; O'Brien, R; Roderick, S; Bell, L; Poulsen, P; Eade, T; Booth, J; Keall, P; Nguyen, DTPublished 2021Purpose: For patients with locally advanced cancer, multiple targets are treated simultaneously with radiotherapy. Differential motion between targets can compromise the treatment accuracy, yet there are currently no methods ...Open AccessArticle -
Anatomical Deformation Due to Horizontal Rotation: Towards Gantry-Free Radiation Therapy
Buckley, J; Rai, R; Liney, G; Dowling, J; Holloway, L; Metcalfe, P; Keall, PPublished 2019-01-01Gantry-free radiation therapy systems may be simpler and more cost effective, particularly for MRI-guided photon or hadron therapy. This study aims to understand and quantify anatomical deformations caused by horizontal ...Open AccessArticle -
Audiovisual Biofeedback Improves Cine-Magnetic Resonance Imaging Measured Lung Tumor Motion Consistency.
Lee, D; Greer, PB; Ludbrook, J; Arm, J; Hunter, P; Pollock, S; Makhija, K; O'Brien, RT; Kim, T; Keall, PPublished 2016-03-01PURPOSE: To assess the impact of an audiovisual (AV) biofeedback on intra- and interfraction tumor motion for lung cancer patients. METHODS AND MATERIALS: Lung tumor motion was investigated in 9 lung cancer patients who ...Open AccessArticle -
Audiovisual biofeedback improves the correlation between internal/external surrogate motion and lung tumor motion.
Lee, D; Greer, PB; Paganelli, C; Ludbrook, JJ; Kim, T; Keall, PPublished 2018-03-01PURPOSE: Breathing management can reduce breath-to-breath (intrafraction) and day-by-day (interfraction) variability in breathing motion while utilizing the respiratory motion of internal and external surrogates for ...Open AccessArticle -
An augmented correlation framework for the estimation of tumour translational and rotational motion during external beam radiotherapy treatments using intermittent monoscopic x-ray imaging and an external respiratory signal.
Nguyen, DT; Booth, JT; Caillet, V; Hardcastle, N; Briggs, A; Hadad, C; Eade, T; O'Brien, R; Keall, PPublished 2018-10-01Increasing evidence shows that intrafraction tumour motion monitoring must include both six degrees of freedom (6DoF): 3D translations and 3D rotations. Existing real-time algorithms for 6DoF target motion estimation require ...Open AccessArticle -
The Australian magnetic resonance imaging-linac program.
Keall, P; Barton, M; Crozier, SPublished 2014-07-01The Australian magnetic resonance imaging (MRI)-Linac program is a $16-million government-funded project to advance the science and clinical practice of exquisite real-time anatomical and physiological adaptive cancer ...Open AccessArticle -
Both four-dimensional computed tomography and four-dimensional cone beam computed tomography under-predict lung target motion during radiotherapy.
Steiner, E; Shieh, CC; Caillet, V; Booth, J; O'Brien, R; Briggs, A; Hardcastle, N; Jayamanne, D; Szmura, K; Eade, T; Keall, PPublished 2019-06-01BACKGROUND AND PURPOSE: To test the hypothesis that 4DCT and 4DCBCT-measured target motion ranges predict target motion ranges during lung cancer SABR. MATERIALS AND METHODS: Ten lung SABR patients were implanted with ...Open AccessArticle -
Breathing guidance in radiation oncology and radiology: A systematic review of patient and healthy volunteer studies.
Pollock, S; Keall, PPublished 2015-09-01PURPOSE: The advent of image-guided radiation therapy has led to dramatic improvements in the accuracy of treatment delivery in radiotherapy. Such advancements have highlighted the deleterious impact tumor motion can ...Open AccessArticle -
Cardiac radioablation for atrial fibrillation: Target motion characterization and treatment delivery considerations.
Lydiard, S; Pontre, B; Lowe, B; Ball, H; Sasso, G; Keall, PPublished 2021Purpose: The safe delivery of cardiac radioablation (CR) for atrial fibrillation (AF) is challenged by multi-direction target motion, cardiac rate variability, target proximity to critical structures, and the importance ...Open AccessArticle -
A CBCT study of the gravity-induced movement in rotating rabbits.
Barber, J; Shieh, CC; Counter, W; Sykes, J; Bennett, P; Ahern, V; Corde, S; Heng, SM; White, P; Jackson, M; Liu, P; Keall, P; Feain, IPublished 2018-05-01Fixed-beam radiotherapy systems with subjects rotating about a longitudinal (horizontal) axis are subject to gravity-induced motion. Limited reports on the degree of this motion, and any deformation, has been reported ...Open AccessArticle -
Changes in Regional Ventilation During Treatment and Dosimetric Advantages of CT Ventilation Image Guided Radiation Therapy for Locally Advanced Lung Cancer
Yamamoto, T; Kabus, S; Bal, M; Bzdusek, K; Keall, P; Wright, C; Benedict, SH; Daly, MEPublished 2018-11-15PURPOSE: Lung functional image guided radiation therapy (RT) that avoids irradiating highly functional regions has potential to reduce pulmonary toxicity following RT. Tumor regression during RT is common, leading to ...Open AccessArticle -
Commissioning and quality assurance for VMAT delivery systems: An efficient time-resolved system using real-time EPID imaging.
Zwan, BJ; Barnes, MP; Hindmarsh, J; Lim, SB; Lovelock, DM; Fuangrod, T; O'Connor, DJ; Keall, P; Greer, PBPublished 2017-08-01PURPOSE: An ideal commissioning and quality assurance (QA) program for Volumetric Modulated Arc Therapy (VMAT) delivery systems should assess the performance of each individual dynamic component as a function of gantry ...Open AccessArticle -
A comparison of gantry-mounted x-ray-based real-time target tracking methods.
Montanaro, T; Nguyen, DT; Keall, P; Booth, J; Caillet, V; Eade, T; Hadad, C; Shieh, CCPublished 2018-03-01PURPOSE: Most modern radiotherapy machines are built with a 2D kV imaging system. Combining this imaging system with a 2D-3D inference method would allow for a ready-made option for real-time 3D tumor tracking. This work ...Open AccessArticle -
Cone-beam CT reconstruction with gravity-induced motion.
Shieh, CC; Barber, J; Counter, W; Sykes, J; Bennett, P; Heng, SM; White, P; Corde, S; Jackson, M; Ahern, V; Feain, I; O'Brien, R; Keall, PPublished 2018-10-01Fixed-gantry cone-beam computed tomography (CBCT), where the imaging hardware is fixed while the subject is continuously rotated 360° in the horizontal position, has implications for building compact and affordable ...Open AccessArticle -
CT ventilation imaging derived from breath hold CT exhibits good regional accuracy with Galligas PET.
Eslick, EM; Kipritidis, J; Gradinscak, D; Stevens, MJ; Bailey, DL; Harris, B; Booth, JT; Keall, PPublished 2018-05-01BACKGROUND AND PURPOSE: CT ventilation imaging (CTVI) derived from four dimensional CT (4DCT) has shown only moderate spatial accuracy in humans due to 4DCT image artefacts. Here we assess the accuracy of an improved CTVI ...Open AccessArticle -
Deep learning enables MV-based real-time image guided radiation therapy for prostate cancer patients.
Chrystall, D; Mylonas, A; Hewson, E; Martin, J; Keall, P; Booth, J; Nguyen, DTPublished 2023Objective. Using MV images for real-time image guided radiation therapy (IGRT) is ideal as it does not require additional imaging equipment, adds no additional imaging dose and provides motion data in the treatment beam ...Open AccessArticle
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