Browsing by author "Govendir, Merran"
Sort by:
Title A-Z
-
Assay validation and determination of in vitro binding of mefloquine to plasma proteins from clinically normal and FIP-affected cats
Izes, Aaron M.; Kimble, Benjamin; Norris, Jacqueline M.; Govendir, MerranPublished 2020The antimalarial agent mefloquine is currently being investigated for its potential to inhibit feline coronavirus and feline calicivirus infections. A simple, high pressure liquid chromatography assay was developed to ...Article -
Assessments of feline plasma biochemistry reference intervals for three in-house analysers and a commercial laboratory analyser.
Baral, Randolph M.; Dhand, Navneet K.; Krockenberger, Mark B.; Govendir, MerranPublished 2015-01-01For each species, the manufacturers of in-house analysers (and commercial laboratories) provide standard reference intervals (RIs) that do not account for any differences such as geographical population differences and do ...Open AccessArticle -
Bias in feline plasma biochemistry results between three in-house analysers and a commercial laboratory analyser: results should not be directly compared
Baral, Randolph M.; Dhand, Navneet K.; Morton, John M.; Krockenberger, Mark B.; Govendir, MerranPublished 2015-01-01In-house analysers are commonplace in small animal practices but cannot be calibrated by the operator; therefore, any bias in the generated plasma analyte values cannot be corrected. Guidelines such as grading of renal ...Open AccessArticle -
Biological variation and reference change values of feline plasma biochemistry analytes.
Baral, Randolph M.; Dhand, Navneet K.; Freeman, Kathleen P.; Krockenberger, Mark B.; Govendir, MerranPublished 2014-01-01This is the first report concerning biological variation and reference change values of feline plasma biochemistry components in the peer-reviewed literature. Biological variation refers to inherent physiological variation ...Open AccessArticle -
Comparisons of results between three in-house biochemistry analysers and a commercial laboratory analyser for feline plasma using multiple quality specifications
Baral, Randolph M.; Dhand, Navneet K.; Krockenberger, Mark B.; Govendir, MerranPublished 2015-01-01In-house plasma biochemistry analysis is commonplace in veterinary practice but there are few studies assessing the results from such instruments. Method comparison in human clinical pathology uses results from both precision ...Open AccessArticle -
Pharmacokinetic Profile of Oral Administration of Mefloquine to Clinically Normal Cats: A Preliminary In-Vivo Study of a Potential Treatment for Feline Infectious Peritonitis (FIP)
Yu, Jane; Kimble, Benjamin; Norris, Jacqueline M; Govendir, MerranPublished 2020The pharmacokinetic profile of mefloquine was investigated as a preliminary study towards a potential treatment for feline coronavirus infections (such as feline infectious peritonitis) or feline calicivirus infections. ...Article -
Repeatability of results from three in-house biochemistry analysers and a commercial laboratory analyser used in small animal practice
Baral, Randolph M.; Dhand, Navneet K.; Morton, John M.; Krockenberger, Mark B.; Govendir, MerranPublished 2015-01-01The repeatability (precision) of clinical pathology results is vital for confidence in the measured values. Comparison to biological variation is an accepted standard for instrument/method performance in human clinical ...Open AccessArticle
Sort by:
Title A-Z