Browsing by author "Eisman, JA"
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Conditional deletion of hypothalamic Y2 receptors reverts gonadectomy-induced bone loss in adult mice
Allison, SJ; Baldock, PA; Sainsbury, Amanda; Enriquez, R; Lee, NJ; Lin, EJD; Klugmann, M; During, M; Eisman, JA; Li, M; Pan, LC; Herzog, HPublished 2006-05-01Reduction in levels of sex hormones at menopause in women is associated with two common, major outcomes, the accumula- tion of white adipose tissue, and the progressive loss of bone because of excess osteoclastic bone ...Open AccessArticle -
Critical Interplay Between Neuropeptide Y and Sex Steroid Pathways in Bone and Adipose Tissue Homeostasis
Allison, SJ; Baldock, PA; Enriquez, RF; Lin, EJ; During, M; Gardiner, EM; Eisman, JA; Sainsbury, Amanda; Herzog, HPublished 2009-02-01Open AccessArticle -
Greater Bone Formation of Y2 Knockout Mice Is Associated with Increased Osteoprogenitor Numbers and Altered Y1 Receptor Expression
Lundberg, PA; Allison, SJ; Lee, NJ; Baldock, PA; Brouard, NJ; Rost, S; Enriquez, RF; Sainsbury, Amanda; Lamghari, M; Simmons, P; Eisman, JA; Gardiner, EM; Herzog, HPublished 2007-10-01Germ line or hypothalamus-specific deletion of Y2 receptors in mice results in a doubling of trabecular bone volume. However, the specific mechanism by which deletion of Y2 receptors increases bone mass has not yet been ...Open AccessArticle -
Hypothalamic regulation of cortical bone mass: opposing activity of Y2 receptor and leptin pathways
Baldock, PA; Allison, S; McDonald, MM; Sainsbury, Amanda; Enriquez, RF; Little, DG; Eisman, JA; Gardiner, EM; Herzog, HPublished 2006-07-01Open AccessArticle -
Neuropeptide Y is a critical modulator of Leptin's regulation of cortical bone
Wong, IPL; Nguyen, AD; Khor, EC; Enriquez, RF; Eisman, JA; Sainsbury, Amanda; Herzog, H; Baldock, PAPublished 2013-04-01Open AccessArticle -
Neuropeptide Y Knockout Mice Reveal a Central Role of NPY in the Coordination of Bone Mass to Body Weight
Baldock, PA; Lee, NJ; Driessler, F; Lin, S; Allison, SJ; Stehrer, B; Lin, EJD; Zhang, L; Enriquez, RF; Wong, IPL; McDonald, MM; During, M; Pierroz, DD; Slack, K; Shi, Y; Yulyaningsih, E; Aljianova, A; Little, DG; Ferrari, SL; Sainsbury, Amanda; Eisman, JA; Herzog, HPublished 2009-12-01Changes in whole body energy levels are closely linked to alterations in body weight and bone mass. Here, we show that hypothalamic signals contribute to the regulation of bone mass in a manner consistent with the central ...Open AccessArticle -
Neuropeptide Y mediates the short-term hypometabolic effect of estrogen deficiency in mice
Zengin, A; Nguyen, AD; Wong, IPL; Zhang, L; Enriquez, RF; Eisman, JA; Herzog, H; Baldock, PA; Sainsbury, AmandaPublished 2013-03-01Open AccessArticle -
Novel Role of Y1 Receptors in the Coordinated Regulation of Bone and Energy Homeostasis
Baldock, PA; Allison, SJ; Lundberg, P; Lee, NJ; Slack, S; Lin, EJD; Enriquez, RF; McDonald, MM; Zhang, L; During, MJ; Little, DG; Eisman, JA; Gardiner, EM; Yulyaningsih, E; Lin, S; Herzog, H; Sainsbury, AmandaPublished 2007-10-01The importance of neuropeptide Y (NPY) and Y2 receptors in the regulation of bone and energy homeostasis has recently been demonstrated. However, the contributions of the other Y recep- tors are less clear. Here we show ...Open AccessArticle -
Peptide YY Regulates Bone Remodeling in Mice: A Link between Gut and Skeletal Biology
Wong, IPL; Driessler, F; Khor, EC; Shi, YC; Hormer, B; Nguyen, AD; Enriquez, RF; Eisman, JA; Sainsbury, Amanda; Herzog, H; Baldock, PAPublished 2012-07-01Open AccessArticle
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