Browsing by author "Eade, T"
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4-Dimensional Cone Beam Computed Tomography-Measured Target Motion Underrepresents Actual Motion
Steiner, E; Shieh, CC; Caillet, V; Booth, J; Hardcastle, N; Briggs, A; Jayamanne, D; Haddad, C; Eade, T; Keall, PPublished 2018-11-15PURPOSE: Four-dimensional cone beam computed tomography (4DCBCT) facilitates verification of lung tumor motion before each treatment fraction and enables accurate patient setup in lung stereotactic ablative body radiation ...Open AccessArticle -
The accuracy and precision of Kilovoltage Intrafraction Monitoring (KIM) six degree-of-freedom prostate motion measurements during patient treatments.
Kim, JH; Nguyen, DT; Booth, JT; Huang, CY; Fuangrod, T; Poulsen, P; O'Brien, R; Caillet, V; Eade, T; Kneebone, A; Keall, PPublished 2018-02-01BACKGROUND AND PURPOSE: To perform a quantitative analysis of the accuracy and precision of Kilovoltage Intrafraction Monitoring (KIM) six degree-of-freedom (6DoF) prostate motion measurements during treatments. MATERIAL ...Open AccessArticle -
The Accuracy and Precision of the KIM Motion Monitoring System Used in the Multi-Institutional TROG 15.01 Stereotactic Prostate Ablative Radiotherapy With KIM (SPARK) Trial
Hewson, E; Nguyen, DT; O'Brien, R; Kim, J-H; Montanaro, T; Moodie, T; Greer, P; Hardcastle, N; Eade, T; Kneebone, A; Hruby, G; Hayden, A; Turner, S; Siva, S; Tai, K-H; Hunter, P; Sams, J; Poulsen, P; Booth, J; Martin, J; Keall, PPublished 2019-01-01Purpose: Kilovoltage intrafraction monitoring (KIM) allows for real-time image guidance for tracking tumor motion in six-degrees-of-freedom (6DoF) on a standard linear accelerator. This study assessed the geometric accuracy ...Open AccessArticle -
Adapting to the motion of multiple independent targets using multileaf collimator tracking for locally advanced prostate cancer: Proof of principle simulation study.
Hewson, E; Ge, Y; O'Brien, R; Roderick, S; Bell, L; Poulsen, P; Eade, T; Booth, J; Keall, P; Nguyen, DTPublished 2021Purpose: For patients with locally advanced cancer, multiple targets are treated simultaneously with radiotherapy. Differential motion between targets can compromise the treatment accuracy, yet there are currently no methods ...Open AccessArticle -
An augmented correlation framework for the estimation of tumour translational and rotational motion during external beam radiotherapy treatments using intermittent monoscopic x-ray imaging and an external respiratory signal.
Nguyen, DT; Booth, JT; Caillet, V; Hardcastle, N; Briggs, A; Hadad, C; Eade, T; O'Brien, R; Keall, PPublished 2018-10-01Increasing evidence shows that intrafraction tumour motion monitoring must include both six degrees of freedom (6DoF): 3D translations and 3D rotations. Existing real-time algorithms for 6DoF target motion estimation require ...Open AccessArticle -
Both four-dimensional computed tomography and four-dimensional cone beam computed tomography under-predict lung target motion during radiotherapy.
Steiner, E; Shieh, CC; Caillet, V; Booth, J; O'Brien, R; Briggs, A; Hardcastle, N; Jayamanne, D; Szmura, K; Eade, T; Keall, PPublished 2019-06-01BACKGROUND AND PURPOSE: To test the hypothesis that 4DCT and 4DCBCT-measured target motion ranges predict target motion ranges during lung cancer SABR. MATERIALS AND METHODS: Ten lung SABR patients were implanted with ...Open AccessArticle -
A comparison of gantry-mounted x-ray-based real-time target tracking methods.
Montanaro, T; Nguyen, DT; Keall, P; Booth, J; Caillet, V; Eade, T; Hadad, C; Shieh, CCPublished 2018-03-01PURPOSE: Most modern radiotherapy machines are built with a 2D kV imaging system. Combining this imaging system with a 2D-3D inference method would allow for a ready-made option for real-time 3D tumor tracking. This work ...Open AccessArticle -
Electromagnetic-Guided MLC Tracking Radiation Therapy for Prostate Cancer Patients: Prospective Clinical Trial Results.
Keall, P; Colvill, E; O'Brien, R; Caillet, V; Eade, T; Kneebone, A; Hruby, G; Poulsen, PR; Zwan, B; Greer, PB; Booth, JPublished 2018-06-01PURPOSE: To report on the primary and secondary outcomes of a prospective clinical trial of electromagnetic-guided multileaf collimator (MLC) tracking radiation therapy for prostate cancer. METHODS AND MATERIALS: Twenty-eight ...Open AccessArticle -
The first clinical implementation of real-time image-guided adaptive radiotherapy using a standard linear accelerator.
Keall, P; Nguyen, DT; O'Brien, R; Caillet, V; Hewson, E; Poulsen, PR; Bromley, R; Bell, L; Eade, T; Kneebone, A; Martin, J; Booth, JTPublished 2018-04-01PURPOSE: Until now, real-time image guided adaptive radiation therapy (IGART) has been the domain of dedicated cancer radiotherapy systems. The purpose of this study was to clinically implement and investigate real-time ...Open AccessArticle -
The first clinical treatment with kilovoltage intrafraction monitoring (KIM): A real-time image guidance method
Keall, P; Ng, J; O'Brien, R; Colvill, E; Huang, C-Y; Poulsen, P; Fledelius, W; Juneja, P; Simpson, E; Bell, L; Alfieri, F; Eade, T; Kneebone, A; Booth, JPublished 2015-01-01PURPOSE: Kilovoltage intrafraction monitoring (KIM) is a real-time image guidance method that uses widely available radiotherapy technology, i.e., a gantry-mounted x-ray imager. The authors report on the geometric and ...Open AccessArticle -
The first patient treatment of electromagnetic-guided real time adaptive radiotherapy using MLC tracking for lung SABR.
Booth, JT; Caillet, V; Hardcastle, N; O'Brien, R; Szymura, K; Crasta, C; Harris, B; Haddad, C; Eade, T; Keall, PPublished 2016-10-01BACKGROUND AND PURPOSE: Real time adaptive radiotherapy that enables smaller irradiated volumes may reduce pulmonary toxicity. We report on the first patient treatment of electromagnetic-guided real time adaptive radiotherapy ...Open AccessArticle -
Geometric uncertainty analysis of MLC tracking for lung SABR.
Caillet, V; Zwan, B; Briggs, A; Hardcastle, N; Szymura, K; Prodreka, A; O'Brien, R; Harris, BE; Greer, P; Haddad, C; Jayamanne, D; Eade, T; Booth, J; Keall, PPublished 2020Purpose: The purpose of this work was to report on the geometric uncertainty for patients treated with multi-leaf collimator (MLC) tracking for lung SABR to verify the accuracy of the system. Methods: Seventeen patients ...Open AccessArticle -
Quantification of intrafraction prostate motion and its dosimetric effect on VMAT.
Juneja, P; Colvill, E; Kneebone, A; Eade, T; Ng, JA; Thwaites, DI; Keall, P; Kaur, R; Poulsen, P; Booth, JTPublished 2017-06-01Intrafraction prostate motion degrades the accuracy of radiation therapy (RT) delivery. Whilst a number of metrics in the literature have been used to quantify intrafraction prostate motion, it has not been established ...Open AccessArticle -
Quantification of the geometric uncertainty when using implanted markers as a surrogate for lung tumor motion.
Hardcastle, N; Briggs, A; Caillet, V; Angelis, G; Chrystall, D; Jayamanne, D; Shepherd, M; Harris, B; Haddad, C; Eade, T; Keall, P; Booth, JPublished 2021Background: Fiducial markers are used as surrogates for tumor location during radiation therapy treatment. Developments in lung fiducial marker and implantation technology have provided a means to insert markers endobronchially ...Open AccessArticle -
Real-Time 3D Image Guidance Using a Standard LINAC: Measured Motion, Accuracy, and Precision of the First Prospective Clinical Trial of Kilovoltage Intrafraction Monitoring-Guided Gating for Prostate Cancer Radiation Therapy.
Keall, P; Ng, JA; Juneja, P; O'Brien, RT; Huang, CY; Colvill, E; Caillet, V; Simpson, E; Poulsen, PR; Kneebone, A; Eade, T; Booth, JTPublished 2016-04-01PURPOSE: Kilovoltage intrafraction monitoring (KIM) is a new real-time 3-dimensional image guidance method. Unlike previous real-time image guidance methods, KIM uses a standard linear accelerator without any additional ...Open AccessArticle
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