Browsing by author "Booth, JT"
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The accuracy and precision of Kilovoltage Intrafraction Monitoring (KIM) six degree-of-freedom prostate motion measurements during patient treatments.
Kim, JH; Nguyen, DT; Booth, JT; Huang, CY; Fuangrod, T; Poulsen, P; O'Brien, R; Caillet, V; Eade, T; Kneebone, A; Keall, PPublished 2018-02-01BACKGROUND AND PURPOSE: To perform a quantitative analysis of the accuracy and precision of Kilovoltage Intrafraction Monitoring (KIM) six degree-of-freedom (6DoF) prostate motion measurements during treatments. MATERIAL ...Open AccessArticle -
An augmented correlation framework for the estimation of tumour translational and rotational motion during external beam radiotherapy treatments using intermittent monoscopic x-ray imaging and an external respiratory signal.
Nguyen, DT; Booth, JT; Caillet, V; Hardcastle, N; Briggs, A; Hadad, C; Eade, T; O'Brien, R; Keall, PPublished 2018-10-01Increasing evidence shows that intrafraction tumour motion monitoring must include both six degrees of freedom (6DoF): 3D translations and 3D rotations. Existing real-time algorithms for 6DoF target motion estimation require ...Open AccessArticle -
CT ventilation imaging derived from breath hold CT exhibits good regional accuracy with Galligas PET.
Eslick, EM; Kipritidis, J; Gradinscak, D; Stevens, MJ; Bailey, DL; Harris, B; Booth, JT; Keall, PPublished 2018-05-01BACKGROUND AND PURPOSE: CT ventilation imaging (CTVI) derived from four dimensional CT (4DCT) has shown only moderate spatial accuracy in humans due to 4DCT image artefacts. Here we assess the accuracy of an improved CTVI ...Open AccessArticle -
Determining appropriate imaging parameters for kilovoltage intrafraction monitoring: an experimental phantom study.
Wallace, D; Ng, JA; Keall, P; O'Brien, RT; Poulsen, PR; Juneja, P; Booth, JTPublished 2015-06-01Kilovoltage intrafraction monitoring (KIM) utilises the kV imager during treatment for real-time tracking of prostate fiducial markers. However, its effectiveness relies on sufficient image quality for the fiducial tracking ...Open AccessArticle -
The first clinical implementation of a real-time six degree of freedom target tracking system during radiation therapy based on Kilovoltage Intrafraction Monitoring (KIM).
Nguyen, DT; O'Brien, R; Kim, JH; Huang, CY; Wilton, L; Greer, P; Legge, K; Booth, JT; Poulsen, PR; Martin, J; Keall, PPublished 2017-04-01PURPOSE: We present the first clinical implementation of a real-time six-degree of freedom (6DoF) Kilovoltage Intrafraction Monitoring (KIM) system which tracks the cancer target translational and rotational motions during ...Open AccessArticle -
The first clinical implementation of real-time image-guided adaptive radiotherapy using a standard linear accelerator.
Keall, P; Nguyen, DT; O'Brien, R; Caillet, V; Hewson, E; Poulsen, PR; Bromley, R; Bell, L; Eade, T; Kneebone, A; Martin, J; Booth, JTPublished 2018-04-01PURPOSE: Until now, real-time image guided adaptive radiation therapy (IGART) has been the domain of dedicated cancer radiotherapy systems. The purpose of this study was to clinically implement and investigate real-time ...Open AccessArticle -
The first patient treatment of electromagnetic-guided real time adaptive radiotherapy using MLC tracking for lung SABR.
Booth, JT; Caillet, V; Hardcastle, N; O'Brien, R; Szymura, K; Crasta, C; Harris, B; Haddad, C; Eade, T; Keall, PPublished 2016-10-01BACKGROUND AND PURPOSE: Real time adaptive radiotherapy that enables smaller irradiated volumes may reduce pulmonary toxicity. We report on the first patient treatment of electromagnetic-guided real time adaptive radiotherapy ...Open AccessArticle -
IGRT and motion management during lung SBRT delivery.
Caillet, V; Booth, JT; Keall, PPublished 2017-12-01Patient motion can cause misalignment of the tumour and toxicities to the healthy lung tissue during lung stereotactic body radiation therapy (SBRT). Any deviations from the reference setup can miss the target and have ...Open AccessArticle -
An interdimensional correlation framework for real-time estimation of six degree of freedom target motion using a single x-ray imager during radiotherapy.
Nguyen, DT; Bertholet, J; Kim, JH; O'Brien, R; Booth, JT; Poulsen, PR; Keall, PPublished 2017-12-01Increasing evidence suggests that intrafraction tumour motion monitoring needs to include both 3D translations and 3D rotations. Presently, methods to estimate the rotation motion require the 3D translation of the target ...Open AccessArticle -
MLC tracking for lung SABR reduces planning target volumes and dose to organs at risk.
Caillet, V; Keall, P; Colvill, E; Hardcastle, N; O'Brien, R; Szymura, K; Booth, JTPublished 2017-07-01PURPOSE: Assess the dosimetric impact of multi-leaf collimator (MLC) tracking and mid-ventilation (midV) planning compared with the internal target volume (ITV)-based planning approach for lung Stereotactic Ablative Body ...Open AccessArticle -
Multileaf Collimator Tracking Improves Dose Delivery for Prostate Cancer Radiation Therapy: Results of the First Clinical Trial.
Colvill, E; Booth, JT; O'Brien, RT; Eade, TN; Kneebone, AB; Poulsen, PR; Keall, PPublished 2015-08-01PURPOSE: To test the hypothesis that multileaf collimator (MLC) tracking improves the consistency between the planned and delivered dose compared with the dose without MLC tracking, in the setting of a prostate cancer ...Open AccessArticle -
Optimising multi-target multileaf collimator tracking using real-time dose for locally advanced prostate cancer patients.
Hewson, E; Nguyen, DT; Le, A; Booth, JT; Keall, P; Mejnertsen, LPublished 2022Objective. The accuracy of radiotherapy for patients with locally advanced cancer is compromised by independent motion of multiple targets. To date, MLC tracking approaches have used 2D geometric optimisation where the MLC ...Open AccessArticle -
Performance assessment of a programmable five degrees-of-freedom motion platform for quality assurance of motion management techniques in radiotherapy.
Huang, CY; Keall, P; Rice, A; Colvill, E; Ng, JA; Booth, JTPublished 2017-09-01Inter-fraction and intra-fraction motion management methods are increasingly applied clinically and require the development of advanced motion platforms to facilitate testing and quality assurance program development. The ...Open AccessArticle -
Quality assurance for the clinical implementation of kilovoltage intrafraction monitoring for prostate cancer VMAT.
Ng, J; Booth, JT; O'Brien, RT; Colvill, E; Huang, CY; Poulsen, PR; Keall, PPublished 2014-11-01PURPOSE: Kilovoltage intrafraction monitoring (KIM) is a real-time 3D tumor monitoring system for cancer radiotherapy. KIM uses the commonly available gantry-mounted x-ray imager as input, making this method potentially ...Open AccessArticle -
Quantification of intrafraction prostate motion and its dosimetric effect on VMAT.
Juneja, P; Colvill, E; Kneebone, A; Eade, T; Ng, JA; Thwaites, DI; Keall, P; Kaur, R; Poulsen, P; Booth, JTPublished 2017-06-01Intrafraction prostate motion degrades the accuracy of radiation therapy (RT) delivery. Whilst a number of metrics in the literature have been used to quantify intrafraction prostate motion, it has not been established ...Open AccessArticle -
Real-Time 3D Image Guidance Using a Standard LINAC: Measured Motion, Accuracy, and Precision of the First Prospective Clinical Trial of Kilovoltage Intrafraction Monitoring-Guided Gating for Prostate Cancer Radiation Therapy.
Keall, P; Ng, JA; Juneja, P; O'Brien, RT; Huang, CY; Colvill, E; Caillet, V; Simpson, E; Poulsen, PR; Kneebone, A; Eade, T; Booth, JTPublished 2016-04-01PURPOSE: Kilovoltage intrafraction monitoring (KIM) is a new real-time 3-dimensional image guidance method. Unlike previous real-time image guidance methods, KIM uses a standard linear accelerator without any additional ...Open AccessArticle -
A six-degree-of-freedom robotic motion system for quality assurance of real-time image-guided radiotherapy.
Alnaghy, S; Kyme, A; Caillet, V; Nguyen, DT; O'Brien, R; Booth, JT; Keall, PPublished 2019-03-21In this study we develop and characterise a six degree-of-freedom (6 DoF) robotic motion system for quality assurance of real-time image-guided radiotherapy techniques. The system consists of a commercially available robotic ...Open AccessArticle -
Technical Note: Real-time image-guided adaptive radiotherapy of a rigid target for a prototype fixed beam radiotherapy system.
Liu, P; Nguyen, DT; Feain, I; O'Brien, R; Keall, P; Booth, JTPublished 2018-10-01PURPOSE: Fixed beam radiotherapy systems utilize couch movement and rotation instead of gantry rotation in order to simplify linear accelerator design. We investigate the ability to deliver fixed beam treatments with the ...Open AccessArticle
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