Browsing by author "Booth, J"
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4-Dimensional Cone Beam Computed Tomography-Measured Target Motion Underrepresents Actual Motion
Steiner, E; Shieh, CC; Caillet, V; Booth, J; Hardcastle, N; Briggs, A; Jayamanne, D; Haddad, C; Eade, T; Keall, PPublished 2018-11-15PURPOSE: Four-dimensional cone beam computed tomography (4DCBCT) facilitates verification of lung tumor motion before each treatment fraction and enables accurate patient setup in lung stereotactic ablative body radiation ...Open AccessArticle -
The Accuracy and Precision of the KIM Motion Monitoring System Used in the Multi-Institutional TROG 15.01 Stereotactic Prostate Ablative Radiotherapy With KIM (SPARK) Trial
Hewson, E; Nguyen, DT; O'Brien, R; Kim, J-H; Montanaro, T; Moodie, T; Greer, P; Hardcastle, N; Eade, T; Kneebone, A; Hruby, G; Hayden, A; Turner, S; Siva, S; Tai, K-H; Hunter, P; Sams, J; Poulsen, P; Booth, J; Martin, J; Keall, PPublished 2019-01-01Purpose: Kilovoltage intrafraction monitoring (KIM) allows for real-time image guidance for tracking tumor motion in six-degrees-of-freedom (6DoF) on a standard linear accelerator. This study assessed the geometric accuracy ...Open AccessArticle -
Adapting to the motion of multiple independent targets using multileaf collimator tracking for locally advanced prostate cancer: Proof of principle simulation study.
Hewson, E; Ge, Y; O'Brien, R; Roderick, S; Bell, L; Poulsen, P; Eade, T; Booth, J; Keall, P; Nguyen, DTPublished 2021Purpose: For patients with locally advanced cancer, multiple targets are treated simultaneously with radiotherapy. Differential motion between targets can compromise the treatment accuracy, yet there are currently no methods ...Open AccessArticle -
Both four-dimensional computed tomography and four-dimensional cone beam computed tomography under-predict lung target motion during radiotherapy.
Steiner, E; Shieh, CC; Caillet, V; Booth, J; O'Brien, R; Briggs, A; Hardcastle, N; Jayamanne, D; Szmura, K; Eade, T; Keall, PPublished 2019-06-01BACKGROUND AND PURPOSE: To test the hypothesis that 4DCT and 4DCBCT-measured target motion ranges predict target motion ranges during lung cancer SABR. MATERIALS AND METHODS: Ten lung SABR patients were implanted with ...Open AccessArticle -
A comparison of gantry-mounted x-ray-based real-time target tracking methods.
Montanaro, T; Nguyen, DT; Keall, P; Booth, J; Caillet, V; Eade, T; Hadad, C; Shieh, CCPublished 2018-03-01PURPOSE: Most modern radiotherapy machines are built with a 2D kV imaging system. Combining this imaging system with a 2D-3D inference method would allow for a ready-made option for real-time 3D tumor tracking. This work ...Open AccessArticle -
Deep learning enables MV-based real-time image guided radiation therapy for prostate cancer patients.
Chrystall, D; Mylonas, A; Hewson, E; Martin, J; Keall, P; Booth, J; Nguyen, DTPublished 2023Objective. Using MV images for real-time image guided radiation therapy (IGRT) is ideal as it does not require additional imaging equipment, adds no additional imaging dose and provides motion data in the treatment beam ...Open AccessArticle -
DMLC tracking and gating can improve dose coverage for prostate VMAT
Colvill, E; Poulsen, P; Booth, J; O'Brien, R; Ng, J; Keall, PPublished 2014-09-01PURPOSE: To assess and compare the dosimetric impact of dynamic multileaf collimator (DMLC) tracking and gating as motion correction strategies to account for intrafraction motion during conventionally fractionated ...Open AccessArticle -
Dose-based optimisation for multi-leaf collimator tracking during radiation therapy.
Mejnertsen, L; Hewson, E; Nguyen, DT; Booth, J; Keall, PPublished 2021Motion in the patient anatomy causes a reduction in dose delivered to the target, while increasing dose to healthy tissue. Multi-leaf collimator (MLC) tracking has been clinically implemented to adapt dose delivery to ...Open AccessArticle -
Electromagnetic-Guided MLC Tracking Radiation Therapy for Prostate Cancer Patients: Prospective Clinical Trial Results.
Keall, P; Colvill, E; O'Brien, R; Caillet, V; Eade, T; Kneebone, A; Hruby, G; Poulsen, PR; Zwan, B; Greer, PB; Booth, JPublished 2018-06-01PURPOSE: To report on the primary and secondary outcomes of a prospective clinical trial of electromagnetic-guided multileaf collimator (MLC) tracking radiation therapy for prostate cancer. METHODS AND MATERIALS: Twenty-eight ...Open AccessArticle -
Evaluation of deep learning based implanted fiducial markers tracking in pancreatic cancer patients
Ahmed, A; Gargett, M; Madden, L; Mylonas, A; Chrystall, D; Brown, R; Briggs, A; Nguyen, T; Keall, P; Kneebone, A; Hruby, G; Booth, JPublished 2023Real-time target position verification during pancreas stereotactic body radiation therapy (SBRT) is important for the detection of unplanned tumour motions. Fast and accurate fiducial marker segmentation is a Requirement ...Open AccessArticle -
The first clinical treatment with kilovoltage intrafraction monitoring (KIM): A real-time image guidance method
Keall, P; Ng, J; O'Brien, R; Colvill, E; Huang, C-Y; Poulsen, P; Fledelius, W; Juneja, P; Simpson, E; Bell, L; Alfieri, F; Eade, T; Kneebone, A; Booth, JPublished 2015-01-01PURPOSE: Kilovoltage intrafraction monitoring (KIM) is a real-time image guidance method that uses widely available radiotherapy technology, i.e., a gantry-mounted x-ray imager. The authors report on the geometric and ...Open AccessArticle -
The first prospective implementation of markerless lung target tracking in an experimental quality assurance procedure on a standard linear accelerator.
Mueller, M; Zolfaghari, R; Briggs, A; Furtado, H; Booth, J; Keall, P; Nguyen, D; O'Brien, R; Shieh, CCPublished 2020-01-01The ability to track tumour motion without implanted markers on a standard linear accelerator (linac) could enable wide access to real-time adaptive radiotherapy for cancer patients. We previously have retrospectively ...Open AccessArticle -
Geometric uncertainty analysis of MLC tracking for lung SABR.
Caillet, V; Zwan, B; Briggs, A; Hardcastle, N; Szymura, K; Prodreka, A; O'Brien, R; Harris, BE; Greer, P; Haddad, C; Jayamanne, D; Eade, T; Booth, J; Keall, PPublished 2020Purpose: The purpose of this work was to report on the geometric uncertainty for patients treated with multi-leaf collimator (MLC) tracking for lung SABR to verify the accuracy of the system. Methods: Seventeen patients ...Open AccessArticle -
Investigating multi-leaf collimator tracking in stereotactic arrhythmic radioablation (STAR) treatments for atrial fibrillation.
Lydiard, S; Caillet, V; Ipsen, S; O'Brien, R; Blanck, O; Poulsen, PR; Booth, J; Keall, PPublished 2018-09-01Stereotactic arrhythmia radioablation (STAR) is an emerging treatment option for atrial fibrillation (AF). However, it faces possibly the most challenging motion compensation scenario: both respiratory and cardiac motion. ...Open AccessArticle -
MagicPlate-512: A 2D silicon detector array for quality assurance of stereotactic motion adaptive radiotherapy.
Petasecca, M; Newall, M; Booth, J; Duncan, M; Aldosari, A; Fuduli, I; Espinoza, A; Porumb, C; Guatellli, S; Metcafe, P; Colvill, E; Cammarano, D; Carolan, M; Oborn, B; Lerch, M; Perevertaylo, V; Keall, P; Rosenfeld, APublished 2015-06-01PURPOSE: Spatial and temporal resolutions are two of the most important features for quality assurance instrumentation of motion adaptive radiotherapy modalities. The goal of this work is to characterize the performance ...Open AccessArticle -
Quantification of the geometric uncertainty when using implanted markers as a surrogate for lung tumor motion.
Hardcastle, N; Briggs, A; Caillet, V; Angelis, G; Chrystall, D; Jayamanne, D; Shepherd, M; Harris, B; Haddad, C; Eade, T; Keall, P; Booth, JPublished 2021Background: Fiducial markers are used as surrogates for tumor location during radiation therapy treatment. Developments in lung fiducial marker and implantation technology have provided a means to insert markers endobronchially ...Open AccessArticle -
Quantifying the accuracy and precision of a novel real-time 6 degree-of-freedom kilovoltage intrafraction monitoring (KIM) target tracking system.
Kim, JH; Nguyen, DT; Huang, CY; Fuangrod, T; Caillet, V; O'Brien, R; Poulsen, P; Booth, J; Keall, PPublished 2017-06-01Target rotation can considerably impact the delivered radiotherapy dose depending on the tumour shape. More accurate tumour pose during radiotherapy treatment can be acquired through tracking in 6 degrees-of-freedom (6 ...Open AccessArticle -
Real-time direct diaphragm tracking using kV imaging on a standard linear accelerator.
Hindley, N; Keall, P; Booth, J; Shieh, C-CPublished 2019-01-01Purpose: As the predominant driver of respiratory motion, the diaphragm represents a key surrogate for motion management during the irradiation of thoracic cancers. Existing approaches to diaphragm tracking often produce ...Open AccessArticle -
See, Think, and Act: Real-Time Adaptive Radiotherapy.
Keall, P; Poulsen, P; Booth, JPublished 2019-01-01The world is embracing the information age, with real-time data at hand to assist with many decisions. Similarly, in cancer radiotherapy we are inexorably moving toward using information in a smarter and faster fashion, ...Open AccessArticle -
Six degrees-of-freedom prostate and lung tumor motion measurements using Kilovoltage intrafraction monitoring.
Huang, CY; Tehrani, JN; Ng, JA; Booth, J; Keall, PPublished 2015-02-01PURPOSE: Tumor positional uncertainty has been identified as a major issue that deteriorates the efficacy of radiation therapy. Tumor rotational movement, which is not well understood, can result in significant geometric ...Open AccessArticle
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