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    • Detection of Alternative Lengthening of Telomeres in Telomerase-Positive Cancers 

      Lee, Joyce Hiu Yan (University of Sydney Sydney Medicine School Children’s Medical Research Institute, 2017-04-12)
      Immortalisation is a hallmark of cancer and requires activation of a telomere lengthening mechanism (TLM) to counteract natural telomere shortening. There are two TLMs: telomerase, reported in 85% of cancers, and Alternative ...