Browsing by subject "B cells"
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Antibody Test Validation and Immunophenotypic Characterisation of B Cells in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease
Published 2023Autoimmunity against myelin contributes to the pathogenesis of inflammatory central nervous system (CNS) demyelination. Myelin oligodendrocyte glycoprotein (MOG) has been a candidate autoantigen in demyelinating disorders. ...Thesis -
Chemokine receptor expression in B-cell lymphoproliferative disorders
Published 2006Chemokine receptors are expressed by many cells, including lymphoid cells, and function to mediate cell trafficking and localisation. Normal B cells have been reported to express CXCR3, CXCR4, CXCRS, CCR6 and CCR7. However, ...Thesis -
Understanding the role of B cells in the pathogenesis of Inflammatory Bowel Disease
Published 2024Inflammatory Bowel Disease (IBD) is a chronic relapsing-remitting disease comprising of two broad phenotypes: Ulcerative Colitis (UC) and Crohn's Disease (CD). The worldwide prevalence and incidence of IBD is on the rise ...Thesis