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    • Serum Levels of Human MIC-1/GDF15 Vary in a Diurnal Pattern, Do Not Display a Profile Suggestive of a Satiety Factor and Are Related to BMI 

      Tsai, VWW; Macia, L; Feinle-Bisset, C; Manadhar, R; Astrup, A; Raben, AB; Lorenzen, JK; Schmidt, PT; Wiklund, F; Pedersen, NL; Campbell, L; Kriketos, A; Xu, A; Pengcheng, Z; Jia, W; Curni, PMG; Angstmann, CN; Lee-Ng, M; Zhang, HP; Marquis, CP; Husaini, Y; Berlinger, C; Lin, S; Herzog, H; Brown, DA; Sainsbury, Amanda; Breit, SN (PLoS ONE, 2015-07)
      The TGF-b superfamily cytokine MIC-1/GDF15 circulates in the blood of healthy humans. Its levels rise substantially in cancer and other diseases and this may sometimes lead to development of an anorexia/cachexia syndrome. ...