README FILE FOR: RAW DATA FOR ACUTE PHASE PROTEIN FIP MANUSCRIPT
RESEARCH DATA, SYDNEY SCHOOL OF VETERINARY SCIENCE, THE UNIVERSITY OF SYDNEY
***********************************************DATA CREATORS************************************************

CREATORS:	[Sally Coggins]
CONTRIBUTORS:	[Jacqueline Norris, Natalie Courtman, Evelyn Hall]
CONTACT:	[sally.coggins@sydney.edu.au]

***********************************************DATA FILES*********************************************************

FILE NAMES:		[APP Manuscript Raw Data]
ACRONYMS/CODES:	[A:G - Albumin-to-globulin ratio; Alb - Albumin; Glob - Globulin; TBil - Total bilirubin; PCV - Packed cell volume; Leuk - Leukocytes; Neut - Neutrophils; Lymph - Lymphocytes; SAA - Serum amyloid A; AGP - Alpha 1 acid glycoprotein; Hapto - Haptoglobin; Wk - Week]
FOLDER STRUCTURE:	[Excel Spreadsheet. Sheet 1 – CatsByWkTx shows raw data for each cat code by week of treatment for key biochemical and hematology parameters; Sheet 2 – Heat Map Final shows how A;G; AGP; SAA and Hapto results are displayed as heatmaps for final publication]
RELATED FILES:	NA

***********************************************DATA SOURCES*****************************************************

WHERE:		[Australia, The University of Sydney]
WHEN:			[2021 - 2023]
HOW:	[De-identified Cat Data collected as per: https://onlinelibrary.wiley.com/doi/10.1111/jvim.16803]
RESOURCES:		NA

**********************************************DATA DEFINITIONS****************************************************

VARIABLES:		[NA]
CODES:		[Missing data are blank cells]
UNITS:	[Cat - Identifier; Week/Wk - Week number; Tx Protocol - Treatment protocol (1 = low dose, Protocol 1; 2 = high dose, either RDV only or RDV/GS, Protocols 2 or 3); Simple Remission - Y = 1, N = 0; AlbGlob - Albumin:Globulin ratio (≥0.6 = normal; 0.4-0.6 = equivocal; <0.4 = abnormal); Alb:Glob Interpretation - L = Low, E = Equivocal, H = High; Protein (63-88 g/L); Protein Interpretation - L = Low, N = Normal, H = High; Alb (27-40 g/L); Albumin Interpretation - L = Low, N = Normal, H = High; Glob (32-52 g/L); Globulin Interpretation - L = Low, N = Normal, H = High; Total Bilirubin (0.2-4.2 µmol/L); Total Bilirubin Interpretation - L = Low, N = Normal, H = High; PCV (0.30-0.45 L/L); PCV Interpretation - L = Low, N = Normal, H = High; Leuk (2–14 ×10⁹/L); Leukocyte Interpretation - L = Low, N = Normal, H = High; Neut (1.88-10.26 ×10⁹/L); Neutrophil Interpretation - L = Low, N = Normal, H = High; Lymph - Lymphocyte count; Lymphocyte Interpretation - L = Low, N = Normal, H = High; SAA (µg/mL; <5 converted to 2.5); SAA Interpretation - L = Low/Normal (<5 µg/mL), E = Equivocal (5-10 µg/mL), H = High (>10 µg/mL); AGP (µg/mL); AGP Interpretation - H = High (>354.7 µg/mL), E = Equivocal (300.2–345.7 µg/mL), L = Low/Normal (<300.1 µg/mL); Hapto (0.7-2.0 mg/mL)]

**********************************************TECHNICAL REQUIREMENTS**********************************************

HARDWARE:		[NA]
SOFTWARE:		[Microsoft Excel]
FILE FORMATS:	[Microsoft Excel]